What are the side effects of nmn, 2019 so far there have been 3 cases of nmn side effects, they appear side effects **** the same point: did not comply with the "W + NMN quality management international ten core standards", chose the unqualified nmn. so what is nmn he has to comply with what kind of quality management standards to be a qualified product?
What is nmn?
nmn, referred to as nicotinamide nanoribonucleotide, is also the precursor of coenzymes NAD contained in the human body, which exists in all biological cells. nmn is a substance originally produced naturally in the human body, but with the decline in the body's ability to generate, and gradually lose the ability to repair. nmn (ACMETEA W + NMN) is a substance that can act on the genetic factors for longevity, and, therefore, the his effect in anti-aging can be expected. At present, the research on nmn is carried out all over the world, not only the anti-aging phenomenon, but also many cases that cannot be completely treated by modern science so far, nmn has an improvement effect on them, so the research on nmn has gained a lot of attention.
Does nmn have any side effects? It happens because we don't take it seriously enough.
Then the main reason for the feedback reflecting the side effects of taking nmn is that there is no reference to the W+NMN International Ten Core Standards for Quality Management, and the incidence of side effects increases. So please strictly refer to the W+NMN Quality Management International Ten Core Standards to avoid the occurrence of harm.
NMN in the choice, need to pay attention to a few points: 1, origin (the United States, France, Japan, Hong Kong) 2, purity (70% 80% 98% 99% for the optional index) 3, content (3000, 6000, 9000, 12000, 12000 at present, 12000 is the optional index) 4, the international certification (single-country certification and dual-country certification, dual-country certification of the dual dual-trial, is the Currently safe and reliable) 5, the production process 6, quality management, from these aspects of the rational choice of NMN, is the formal scientific way!
So please refer strictly to the "W + NMN quality management of the international ten core standards) (NMN is what NMN what are the side effects of the big brother IQ tax!)
W+NMN quality management international ten core standards
1, quality management system: NMN must comply with the "OULF" European Union law testing qualified and "FDA U.S. Food and Drug Administration" certification, in addition to the labeling of the name of the commodity, but also need to label all the ingredients content and NMN purity of the word, you need to label the country of origin and distribution country.
2, production process management system: high and the production process affects NMN live form. It is not recommended to use "chemical extraction method" to avoid chemical residues.
3, content management system: relative NMN content mg/bottle ≥ 12000, absorption directly to the small intestine, enteric absorption is 20% of gastric absorption.
4, efficiency management system: to examine the authenticity and purity of raw materials.
5, absorption management system: the use of enteric absorption, enhance the absorption rate and absorption threshold.
6, activity management system: the number of molecules that convert NAD+ per unit dose (per 100 grams), NMN molecules can easily pass through the cell membrane and enter the inside of the cell to increase the NMN content of the human body within 15 minutes and rapidly increase the level of NAD+.
7, the use of the scope of management system: adults ( pregnancy, lactating women are prohibited ).
8, safety management system: production process, raw material collection, "OULF" OULF standard basic system, factory OULF testing, microbial heavy metal exceeding the standard strict examination, generation of technical work of science.
9, raw material management system: most NMN enterprises are single-country certification, and the current dual-country certification of raw materials management is more rigorous and AnTsuen, ACMETEA W + NMN, belongs to the French and U.S. dual-country certification standards of the product.
10, multi-country supervision and management system: "France" "U.S." two countries double supervision. The U.S. FDA has set standards for GMP of dietary supplements, and the European Food Safety Authority (EFSA) has regulations related to the management of food supplements in the European Union.
"W+NMN Quality Management International Top Ten Core Standards"
W+NMN Quality Management International Top Ten Core Standards Details:
One, the quality management system:
NMN must be in line with the "OULF" European Union method of testing qualified and the "FDA U.S. Food and Drug Administration" certification, in addition to the labeling of the name of the product, but also need to mark all the In addition to labeling the trade name, it is also necessary to label the content of all ingredients and NMN purity words, need to label the country of origin and country of distribution.
Second, the production process management system:
Does the production process also affect the health of NMN on the body?
1, the raw material level that is the medical grade raw materials, generally not as a direct oral use;
2, ACMETEA W + NMN's "cold-pressing biological enzyme" production technology, which allows NMN to remain inactivated at low temperatures, and pressed to become a stable capsule, the purity of the NMN will be increased to 99%, more conducive to the preservation and distribution of NMN, which will be more conducive to the preservation and distribution of NMN. 99%, more convenient for preservation and human absorption, in order to maximize the bioavailability of cofactors to support human metabolism, without the need to convert to nicotinamide ribonucleoside (NR) through the SLC12A8 gene, and directly and rapidly converted to NAD + to supplement the level of NAD + in the body, which is the first preparative solution at present.
Three, content management system:
On the issue of NMN daily dosage, the real baffled in the scientific research level of academic support for a statement is that the human body is taking 8 mg of NMN per kg of body weight per day, so that the conversion into a 70 kg adult, then, the daily recommended dosage of 560 mg or so, the daily absorption, consumption, age growth, and so on. The ACMETEA W+ NMN content mg/bottle ≥ 12,000 is able to ensure that the above daily consumption and body reserves.
Currently, the total content of NMN in each bottle is different; NMN3000 is a bottle of 3000mg; NMN6000 is 6000mg/bottle; NMN9000 is 9000mg/bottle; NMN12000 is ACMETEA W+12000mg/bottle, and the content and purity of ACMETEA W+NMN12000 are the highest. NMN12000 has the ability to enhance the level of activation within the tissue, promote NMN12000 content quickly into the cells of each organism, increase the number of NMN to inhibit aging, so that the aging organs to revive, our body is gradually losing function, timely repair. Successfully let the cells reappear alive.
Four, efficiency management system:
Through ACMETEA W + NMN can avoid the edge of the diminishing effect, control the product to maintain the level of efficacy for a long time; to enhance the efficiency of the tricarboxylic acid cycle, so that NMN in the human body to produce more efficacy, but also to avoid the uncontrolled effects of overdose intake; the ability to maintain the rate of absorption, and thus reduce the impact of the human body.
NMN regulates cell survival and death, and maintains the redox state. Recent studies have found that by regulating the level of NMN in the organism, repairing damaged cells in a timely manner, slowing down cell mutation and aging, it also slows down the decline of the human body and reduces diseases, thus achieving the purpose of anti-aging. For cardiovascular and cerebrovascular diseases, neurodegenerative diseases and aging degenerative diseases, etc. have better metallurgical and repair effects; in addition, ACMETEA W + NMN can also participate in and regulate the body's endocrine, play a role in protecting and repairing the function of pancreatic islets, increase the secretion of insulin, prevention and treatment of urolithiasis and obesity and other metabolic diseases.
V. Absorption management system:
Whether the effect of NMN is obvious, the average person on the absorption of nutrients is only 10-20%, the NMN is no exception, when the purity of the NMN increased to 99%, through the ACMETEA W + NMN technology to stabilize the MNM in the stomach in the form of a rapid transmembrane, to avoid destruction of the gastric acid, will be absorbed by ten to twenty-fold enhancement through the Enteric absorption, small intestinal cells on the slc12a8 transporter is specifically responsible for the transfer of NMN into the cell, and then with the blood circulation, will be the body's various organs and tissues of the cell utilization, to ensure that the clinical ACMETEA W + NMN data true.
Currently, several clinical trials of NMN as a treatment for disease have been completed in the first phase of human clinical trials, including Harvard Medical School, and all of them proved to be safe for human beings. In previous animal tests, researchers used 50 times the normal dose and fed mice for six months without finding any negative effects. The U.S. FDA has also certified NMN as a safe food additive.
The key to why you need to take NMN, Sirtuins are a group of proteins that can reverse DNA damage, which reverses aging within your cells at the cellular level, that's why ACMETEA W+NMN has the potential to enhance your ability to age, Sirtuins need two things to facilitate the startup, first they need enough fuel and then they need someone to to step on the gas at startup, that fuel is NAD+, that's where ACMETEA W+NMN comes in, Sirtuins is what we're trying to wake up to, that's what really helps you with anti-aging, to start up Sirtuins proteins you need fuel, that's NAD+, and NMN can provide that fuel but right now your body produces its own NAD+, so why do you need to take NMN to boost your NAD+ levels, and here's the key part, as you get older your NAD+ levels start to drop, which means there's not enough fuel to kickstart your Sirtuins, and that's why when you're getting a little bit older you need to boost your NAD+ levels, and so you do that by taking ACMETEA W + NMN to supplement with NAD+, if you're over 30 it's recommended that you take 1 gram of ACMETEA W+NMN every morning it gets into your cells, it gets into your bloodstream and your cells can absorb it in that will provide your cells with all the fuel they need to kickstart your Sirtuins.
VI. Live Form Management System:
ACMETEA W+NMN converts the number of molecules of NAD+ per unit dose (per 100 grams), the concentration of NMN in the blood gradually increases within 10 minutes, and within 30 minutes, NMN enters into multiple tissues with the bloodstream and synthesizes NAD+ in the tissues to elevate the level of NAD+.
VII, the use of the scope of management system:
1. the elderly, used to assist in improving a variety of geriatric diseases;
2. middle-aged people, to dissolve or alleviate a variety of sub-health problems, such as chronic fatigue, poor sleep, eyesight loss, etc.;
3. stay up all night to accelerate the recovery of the organism;
4. test-takers, to improve the ability to resist stress, to maintain the The person with high radiation dose, such as radiology doctors and nurses, aircrews, to improve the repair ability of genes damaged by radiation;
6. Cancer patients, to help patients repair genes after radiotherapy to improve the immune system, to accelerate the recovery of the body;
7. Cancer patients, to help patients after radiotherapy to repair genes, improve immunity, accelerate the recovery of the body;
7. fitness, to accelerate muscle growth;
8. athletes, to enhance energy levels and reaction speed;
10. smokers, to reduce tobacco addiction;
11. depressed, to enhance the level of dopamine, to change the mood, to increase the blood supply to the brain, and to alleviate the depression caused by the decline of the brain;
12. For middle-aged and old-aged women, it can improve skin health and slow down skin aging;
Eight, AnTsuen management system:
In terms of production process, ACMETEA W+NMN's "cold-pressing biological enzyme" technology, the purity of extracted NMN is as high as 99%, and the content of each bottle can be as high as 12,000mg. ACMETEA W+NMN in the current NMN brand is also the highest content, "OULF" OULF standard basic system, strict compliance with the factory OULF testing, microbial heavy metal exceeds the standard strict review, generation of technical work to extend the scientific.
Nine, raw materials management system:
Numerous NMN manufacturers, raw materials in a single country certification, while the real level of AnTsuen is required to dual-country certification, ACMETEA W + NMN products, belonging to the French and U.S. dual-country certification standards. In terms of raw materials, ACMETEA W+NMN products are certified by both the French and American authorities.
Ten, multinational supervision and management system:
ACMETEA W + NMN meets the U.S. FDA standards for dietary supplements GMP regulations, GMP is a set of mandatory standards applicable to the pharmaceutical, food and other industries, requiring companies to meet the health and quality requirements from the raw materials, personnel, facilities and equipment, the production process, packaging and transportation, quality control, etc., according to the relevant national regulations.
ACMETEA W+NMN complies with the European Union Food Safety Authority (EFSA) EU Food Supplements and OULF regulations. The aim is to ensure that the nutritional and health information provided to consumers on food packaging is accurate and reliable so that consumers do not misinterpret it. The basic purpose of the regulation is to provide legal and regulatory harmonization of nutritional and health claims for food and related functional foods between EU member states in terms of labeling, presentation, advertising, etc., so that related food products can circulate freely between member states;
Everyone ages, and everyone is trying to figure out how to stop it. As we age, fatigue increases, our bones weaken and our health deteriorates, and all kinds of chronic diseases stay with us. Aging is the beginning of many diseases. Unfortunately, we have found a way to cope with aging, but the choice of NMN must comply with the W+NMN Quality Management International Ten Core Standards. In our pursuit of longevity, we must also pay more attention to the safety of the products themselves. Recognize the safest and most reliable quality only