Fungal polysaccharides have strong immunogenicity. Immunogenicity is the ability to stimulate the activation, proliferation and differentiation of immune cells to produce specific antibodies or sensitized lymphocytes. There is no doubt about it.
In nature, many microorganisms are rich in capsular polysaccharide. It is by taking advantage of this that people have developed various antibacterial and antiviral vaccines, such as 23-valent pneumococcal polysaccharide vaccine and meningococcal polysaccharide vaccine. Therefore, polysaccharide itself has immunomodulatory effect.
At present, lentinan and Grifola frondosa polysaccharide have been approved by CFDA for adjuvant treatment of radiotherapy and chemotherapy of digestive tract tumors and adjuvant treatment of immunodeficiency, such as lentinan injection and Grifola frondosa β glucan.
According to literature reports, the research on fungal polysaccharides mainly focuses on the following three aspects: 1. Antitumor fungal polysaccharide does not directly kill tumor cells, but also plays an auxiliary role in tumor treatment by enhancing the immune defense system of patients.
2. Immunoregulation The most significant biological activity of polysaccharide from edible fungi is mainly reflected in immunomodulation. According to literature research, its mechanism includes enhancing macrophage phagocytosis, promoting lymphocyte proliferation, improving humoral immune function and promoting the expression of immune cytokines.
3. The antioxidant research of Yang Lan and others shows that both auricularia auricula polysaccharide and lentinan have antioxidant capacity. Lentinus edodes polysaccharide has a strong ability to scavenge free radicals, and both of them can improve the activities of antioxidant enzymes SOD and GSH in liver to varying degrees.
Fungal polysaccharides are maliciously hyped and exaggerated. First of all, from the results of clinical research, fungal polysaccharides do have the above-mentioned effects, and have been developed into drugs and approved for clinical use.
Secondly, at present, they are all injected, that is, directly hitting the human body, not taking orally. Oral administration must pass through the digestive tract, and immunogenic polysaccharides are broken down into monosaccharides, which has no therapeutic value. I want to remind you that lentinan is not equal to lentinan. The typo needs polishing.
Third, it is inevitable to get sick and go to the hospital in a hurry. We should seek formal treatment. Think about it. If even the hospital doctors can't cure diseases, they can be cured by health care products alone? Logically, it doesn't work.
A word difference, a big difference.
Literature: 1, Lu et al., Immunomodulatory effect and mechanism of polysaccharide from edible fungi, progress in animal medicine, 20 12( 1 1), 104- 108.
2. Study on antioxidant activity of fungal polysaccharides such as Yang Lan, Journal of Guizhou Normal University, 20 17(04), 95-99.
3. Xu, Study on the immunomodulatory mechanism of lentinan, Master thesis (20 14).
4. Wang Lina et al., Study on Antitumor Activity of Compound Medicinal Fungal Polysaccharide, Biotechnology Newsletter, 20 16(06), 888-89 1.
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