Chinese herbal medicine has the functions of nourishing kidney yin, purging fire, improving sleep, promoting fluid production and moistening lung, which can obviously reduce the release of excitatory amino acid transmitters and increase the release of inhibitory amino acid transmitters and β-endorphins, thus inhibiting the functional activities of hypothalamic GnRH neurons and reducing the secretion of GnRH. It can also regulate the development and maturity of bones by regulating the expressions of estrogen receptor α( ERα) and insulin-like growth factor-1 receptor (IGF- 1R) on the growth plate, and regulate the physique of early developmental children who have not reached the treatment stage of GnRHa, thus inhibiting the early arrival of Tiangui and slowing down the development process; For children with precocious puberty who meet the treatment indications of GnRHa, early intervention can be combined with other treatment schemes to induce remission at the onset and consolidate and maintain the curative effect after remission, which is helpful to children.
Children grow up healthily.