Is the IVF in good health?

Many people think that after birth, the physical quality of IVF will be worse than that of naturally conceived children. In fact, so far, there is no evidence that IVF transplantation leads to poor physical fitness of children. The poor physical fitness of children after birth is caused by many factors and has little to do with IVF transplantation. So is the IVF in good health?

Is the test-tube baby in good health? No, compared with normal children, babies born through three generations of IVF technology are healthier because chromosome screening can avoid diseases caused by chromosomes.

Since the birth of 1978, the first test-tube baby in the world, the ethical debate about it has never stopped. As a derivative technology of IVF, Handyside reported the birth of the world's first "third generation IVF" in 1990, which successfully avoided the occurrence of X-linked genetic diseases.

Since then, the application scope of "three generations of test-tube babies" has been further expanded, and some scientists have begun to worry whether artificial selection of embryos will change the evolution of human species and cause potential harm to mankind; Religious people believe that it is blasphemy to human beings to play the role of God and choose embryos.

Technical advantages of the third generation of IVF The third generation of IVF is also called preimplantation genetic diagnosis (PGD), including preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS). Before IVF-ET embryo transfer, the genetic material of the embryo is analyzed to diagnose whether there is abnormality, screen healthy embryo transfer and prevent the spread of genetic diseases.

Compared with the traditional method of fetal gene diagnosis by taking villi or amniotic fluid cells in the first or second trimester, the advantages of the third generation IVF are as follows:

Early detection: diagnosis should be made before embryo implantation in uterus to avoid abortion and induced labor.

Minimal trauma: a small number of tiny cells can be used for diagnosis, which rarely affects the later embryonic development.

High diagnostic rate: At present, the diagnostic rate of embryos is above 90%.

Like prenatal diagnosis and prenatal screening, the genetic diagnosis of the third generation of IVF before embryo implantation is also a way of artificial intervention in pregnancy, and its purpose is consistent with prenatal screening, both of which are aimed at preventing birth defects. The third generation of IVF is actually suitable for everyone and can greatly improve the success rate.

It should be emphasized that although healthy embryos are selected, after embryo transfer, abnormal chromosome changes may occur in the fetus at any stage of life development due to maternal reasons, environment and other factors. Therefore, after the successful conception of the third generation IVF, pregnant women still need routine prenatal examination.