In 1866, Dr. John Langdon Down first described and published the typical signs of Down syndrome, including similar facial features of such children. Therefore, this syndrome is named down syndrome after its name. ?
Modern medicine has confirmed that the incidence of Down syndrome is related to the pregnant age of the mother, and it is an abnormality of chromosome 2 1, which has three types: trisomy, translocation and chimerism. Older pregnant women and aging eggs are important reasons for not separating.
Extended data:
Clinical manifestations of Down syndrome
1, special face: This is the most direct basis for the initial judgment of Down syndrome in life. Children will have symptoms such as wide eye distance, small eye fissure, flat nose root, tongue hypertrophy, frequent tongue spitting and drooling. Moreover, the patient has short stature, short limbs and short fingers.
2. Mental retardation: Mental retardation is also a characteristic clinical manifestation of patients with Down syndrome, and its mental retardation is gradually obvious with age.
3. Delayed sexual development: boys will not have fertility when they grow up, while girls may have menstruation and may have children when they grow up.
4. Others: Congenital heart disease is also a common clinical manifestation of children with Down syndrome, and children are prone to infection, which is caused by the decline of their immune function.
Baidu Encyclopedia-Down Syndrome