What is the domestic anticancer drug worth 1.2 million?

The latest treatment is called CAR-T. Let's answer what CAR-T is first. Everyone knows this cancer cell in our body. Once it expands, what about our immune system? I can't control it. The immune system has many components. For example, the most typical one is called T cell. This kind of T cell is helpless in the face of many cancer cells. This CAR-T is to extract this T cell from your blood and then carry out transgenic technology. On the one hand, add a car to him and let him identify this cancer cell. The second one can give him a lot of amplification and copy T.

Car-t can be used as a drug delivery tool.

We must first understand what cancer is. As long as we live long enough, there is a certain chance of this gene mutation, that is, the ability of normal cells to obtain infinite proliferation, which is called cancer. In fact, most of us have three or five chances to get cancer in our life, but fortunately, our bodies still have immunity, which is called resistance. Then, a small number of cancer cells produced by some early gene mutations were quickly eliminated by our immune system, so most of us can live a healthy life. In a few cases, your immunity is low, and then cancer cells expand rapidly, which will develop into cancer.

For example, you have a flock of sheep and two shepherds. Sheep are our normal cells and shepherds are our T cells. At this time, a large group of wolves suddenly came at night, which were cancer cells. At this time, the shepherd has two shortcomings. The first is that there are too few shepherds. Two shepherds can't deal with dozens or hundreds of wolves anyway. The second wolf is very cunning. They are all wolves in sheep's clothing. The two shepherds can't tell who is a sheep and who is a wolf. So what should we do? Now suddenly there is a good way to pick up your two sheepdogs and give them the ability to distinguish between yang and wolf. At the same time, you can clone each shepherd into dozens or hundreds of shepherds. Finally, after this CAR-T treatment, the two shepherds will become hundreds of shepherds when they come back, and these hundreds of shepherds have very strong fighting capacity and can accurately distinguish which sheep are.

Why is this medicine so expensive? First of all, because the disease is rare, the CAR-T cells reported this time are mainly for a B-cell lymphoma, which is very rare and the research and development cost is very high, so this is why the drug is so expensive, and the cost is increased to ensure the early investment of one of its intellectual property rights. Secondly, his steps are very complicated. He customized your T cells according to each patient's personality, and then made some genetic modification. It is said that the whole step can reach 5600 steps.