Hehe ~ Let's start today's popular science content!
Everyone knows that exercise can strengthen the body, improve immunity and make the body healthy, but why can exercise improve immunity and make the body healthy?
I guess many people don't know this, do they? Okay, this is-showtime!
Below, let's walk into the column "I love science and love me" to explore the real reason why exercise can make you healthy! This column is broadcast under the long-term sponsorship of "Probiotics for China for 20 years-Probiotics for Jin Baihe"!
Scientists are actually curious people. They are curious about the reason why human body exercise can improve immunity, so they have studied this problem.
The first is conjecture. Some scientists have suggested that exercise can improve human immunity because it can transform human intestinal flora in a beneficial direction.
Is that really the case?
So scientists started experiments. First, they do experiments with mice!
Scientists transplanted the feces of exercise and non-exercise mice into the colon of non-exercise sterile mice. These mice live in a sterile environment for a long time and do not belong to their own microbial community.
Subsequently, scientists found that the changes of the flora in recipient mice can reflect the flora in donor mice, and there are obvious differences between infertile mice implanted with feces of two different lifestyles.
The recipient mice (transplanted exercise mice flora) have a high proportion of flora that can produce butyrate, which is a short-chain fatty acid that can improve the health of intestinal bacteria, reduce the inflammation of the host and generate energy. These mice are also more resistant to experimental ulcerative colitis, an inflammatory intestinal disease.
Scientist Woods said that fecal transplantation has an effect. So the hypothetical conclusion is valid!
Subsequently, the research team tracked the changes of intestinal microbial composition in human subjects. During the research, these subjects first changed from a sedentary lifestyle to an athletic lifestyle, and then changed from an athletic lifestyle to a sedentary lifestyle.
The team recruited 18 thin adults who lacked exercise and 14 obese adults, extracted their intestinal microbes and started an exercise program. During this period, they were supervised to do aerobic exercise for six weeks, three times a week for 30 to 60 minutes each time.
After the six-week exercise program, the researchers took samples of intestinal microorganisms from the subjects again. After that, the subjects adopted a lifestyle of not exercising for another six weeks, and finally the researchers sampled their intestinal microorganisms. Throughout the study, the subjects maintained their daily diet.
After exercise, the concentration of short-chain fatty acids (SCFA) in the feces of the subjects increased, especially butyrate. After the subjects returned to an inactive lifestyle, the concentration of SCFA decreased again. The sequencing analysis of microbial groups confirmed that the change of SCFA concentration was directly proportional to the number of microorganisms producing SCFA such as butyric acid.
The results show that the original hypothesis is true! In other words, the real principle of human body exercise to improve immunity is that exercise can help intestinal flora transform in a beneficial direction!
In the experiment, there is a very magical point, that is, the increase of SCFA concentration in thin people is much higher than that in fat people. This may be the reason why fat people have poor immunity.
Of course, the real reason must be explored by scientists!
All right! That's all for this issue. See you next time!
refer to
1, the changes of intestinal microbial community induced by exercise training persist after microbial community establishment, and weaken the response to chemically induced colitis.
DOI: 10. 1080/ 19490976.20 17. 1372077
2. Exercise changes the composition and function of intestinal flora in lean and obese people.
DOI: 10. 1080/ 19490976.20 17. 1372077