Lack of sleep can also disturb the biological clock. Once the normal sleep pattern of human body is constantly destroyed, it will make people mentally unstable, hinder the supply of body functions, cause permanent damage to human organs and physiological tissues, and cause many diseases. On June 8, 2006, the headline article of Yishou Digest published a research conclusion: when sleep deprivation reaches a certain level, it will cause serious harm to the body, including dry skin, slow response, hearing loss, deafness and tinnitus, loss of appetite, obesity, and the incidence of gastric ulcer, heart disease, cold and other diseases will increase.