Relevant data show that 6 million people in the United States are suspected of suffering from "sub-health" every year. In Australia, 37% of the population suffers from this disease. In Asia, the proportion of "sub-health" diseases is higher. According to some data, a new survey conducted by the Japanese Institute of Public Health not long ago found and proved that 35% of the thousands of employees surveyed suffered from chronic fatigue syndrome, and they had a medical history of at least half a year. In Changsha, China, a survey of middle-aged women found that 60% of middle-aged women were in a "sub-health" state. According to the survey of 10 city workers by the Ministry of Health, 48% of them are in a "sub-health" state. According to the statistics of the World Health Organization, the population suffering from "sub-health" diseases is on the rise in many countries and regions. Some experts predict that fatigue is the number one enemy of human health in 2 1 century.