Biotin is one of the B vitamins, also known as vitamin H, vitamin B7, coenzyme R(Coenzyme R) and so on. It is a factor found in the liver during the study of yeast growth factor and rhizobia growth and respiration promoting factor in 1930s, which can prevent and treat depilation and skin damage caused by feeding raw egg protein to rats. Biotin is a member of the water-soluble vitamin B family. Rich in liver, kidney, yeast and milk, it is an important factor for organisms to fix carbon dioxide. It is easy to combine with protein in egg white, and a large amount of crude protein will hinder the absorption of biotin, leading to biotin deficiency, such as depilation, weight loss, dermatitis and so on. Biotin plays an important role in biochemical reaction pathways such as fat synthesis and glycogen production.
Biotin is the savior of baldness, which can not only prevent hair loss and brightness on the top of the head, but also prevent juvenile white hair that is common in modern people. It also plays an important role in keeping skin healthy. As for the efficacy of stabilizing the nervous system, it has not been confirmed yet, but it is really helpful for depression and insomnia.
Biotin is a coenzyme of many carboxylases, and plays the role of CO2 carrier in carboxylase reactions.
1, which constitutes the photosensitive substance in visual acuity cells.
Biotin is oxidized in vivo to form cis-retinoic acid and trans-retinoic acid. There are two kinds of photosensitive cells in human retina, among which rod cells are sensitive to weak light, which is related to dark vision, because rod cells contain rhodopsin, a photosensitive substance, which is composed of eyeball cells and cis-retinoic acid. When vitamin H is deficient, cis retinoic acid can't be supplemented enough, and rod cells can't synthesize enough rhodopsin cells, which leads to night blindness.
2. Maintain the integrity and perfection of epithelial tissue structure. Biotin is a necessary substance to maintain the health of epithelial tissue. Vitamin H deficiency can cause keratinization, hyperplasia and dryness of mucosa and epidermis, leading to dry eye. In severe cases, corneal keratinization is thickened and inflamed, and even perforation leads to blindness. When sebaceous glands and sweat glands are keratinized, the skin is dry, hair follicle papules and hair loss appear. Because the epithelial cells of digestive tract, respiratory tract and urinary tract are not perfect, they are easy to be infected.
3. Enhance the immune response and resistance of the body. Biotin can enhance the body's immune response and anti-infection ability, stabilize the lysosomal membrane of normal tissues, maintain the body's humoral immunity and cellular immunity, and affect the secretion of a series of cytokines. Large doses can promote thymus hyperplasia, just like immune enhancers, which can enhance immunity.
4. Maintain normal growth and development. When biotin is deficient, the reproductive function declines, the bone growth is poor, and the growth and development of embryos and children are hindered.
Can be used for treating arteriosclerosis, apoplexy, lipid metabolism disorder, hypertension, coronary heart disease and blood circulation disorder.
When used in cosmetics, it can improve the circulation speed of blood in skin and blood vessels, and it is easy to mix with grease in the formula within the concentration range of 0. 1%~ 1.0%. Can be used in skin cream, sports liquid, foot pain-relieving ointment, shaving lotion and shampoo.
Physiological function: Biotin and enzyme combine to participate in the fixation and carboxylation of carbon dioxide in vivo, which is related to important metabolic processes in vivo, such as carboxylation of pyruvate to oxaloacetate and carbonylation of acetyl-CoA to malonyl-CoA, and other major biochemical reactions in sugar and fat metabolism. It is also the growth factor of some microorganisms, and a very small amount (0.005 μ g) can make the tested bacteria grow. For example, Streptomyces. Only a little biotin is needed to grow. The daily requirement of human body is about 100 ~ 300 micrograms. There is an avidin in raw egg white, which can combine with biotin, and the combined biotin can not be absorbed by digestive tract. Lead to the lack of biotin in animals, at this time anorexia, glossitis, dandruff dermatitis, hair removal and so on. But there is no shortage of human biotin, which may be due to the fact that intestinal bacteria can synthesize biotin in addition to food sources.
Efficacy: Vitamin H is a key regulatory element for glycogen heterogenesis, fatty acid synthesis and some amino acid metabolism, which can promote the synthesis of some protein by helping to generate energy; At the same time, it can help cells grow, produce fatty acids, metabolize sugar, fat and protein, and contribute to the utilization of vitamin B group; Promote the health of sweat glands, nerve tissues, bone marrow and male gonads; Maintain the normal operation and growth of skin and hair, and relieve the symptoms of eczema and dermatitis; Preventing white hair and alopecia is helpful to treat baldness; Relieve muscle pain; It is really helpful for depression and insomnia; It also participates in the metabolism of vitamin B 12, folic acid and pantothenic acid. Promote urea synthesis and excretion; Improve human immune function.