Can I do non-invasive DNA in pregnancy 19 weeks? It can be done at 19 weeks of pregnancy, but it should be noted that non-invasive DNA examination is only a deformity examination and cannot replace chromosome puncture examination. However, the best time for non-invasive prenatal genetic testing of pregnant women is between 12-26 weeks after pregnancy, which is more accurate and will not cause trauma.
Non-invasive prenatal DNA testing is also called non-invasive prenatal DNA testing and non-invasive fetal chromosome aneuploidy testing. According to the Committee of American College of Obstetrics and Gynecology, an international authoritative academic organization, non-invasive prenatal DNA testing is the most widely used technical name. Non-invasive DNA prenatal detection technology only needs to extract the venous blood of pregnant women, and use the new generation DNA sequencing technology to sequence the free DNA fragments (including fetal free DNA) in pregnant women's peripheral plasma, and analyze the biological information of the sequencing results to obtain the genetic information of the fetus, so as to detect whether the fetus has three major chromosome diseases.
Maternal plasma contains fetal free DNA, which provides a practical basis for this project. Fetal chromosome abnormality will bring slight changes in maternal DNA content, which can be detected by deep sequencing and biological information analysis, providing theoretical basis for the project. A new generation of high-throughput sequencing and information analysis platform provide a technical basis for deep mining of fetal free DNA information in maternal plasma.
Noninvasive DNA is suitable for people. Non-invasive prenatal DNA testing can avoid the risk of abortion and infection caused by invasive diagnosis. The mature performance of DNA sequencing technology ensures the accuracy of the technology. Pregnant women can detect it in more than 12 weeks, and the results of 10 work at sunrise. The following groups apply:
1, old age (age? 35 years old), unwilling to choose pregnant women with invasive prenatal diagnosis.
2. Pregnant women who are unwilling to choose invasive prenatal diagnosis because of the high risk of Tang screening results or the change of single index values.
3. Pregnant women who are unwilling to choose invasive prenatal diagnosis because of the increase of fetal nt value or other anatomical abnormalities during pregnancy.
4. Pregnant women who are not suitable for invasive prenatal diagnosis, such as virus carriers, placenta previa, low placenta, oligohydramnios, RH blood group negative, abortion history, threatened abortion or baby.
5. Pregnant women who fail to culture amniocentesis cells and are unwilling to accept or can no longer make invasive prenatal diagnosis. We hope to exclude fetal 2 1 trisomy, 18 trisomy and1trisomy syndrome, and voluntarily choose pregnant women for non-invasive prenatal testing.
6. Pregnant women with positive serum screening and pregnant women with psychological disorders in prenatal diagnosis. Every couple is at risk of having children with chromosomal diseases. Its occurrence is accidental and random, without warning beforehand, family history and clear toxic contact history, and the incidence rate increases with the age of pregnant women. At present, there is no effective means to treat chromosome diseases.
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