According to the clinical manifestations of sub-health state, it can be divided into the following categories: ① Physical symptoms such as fatigue, sleep disorder or pain are the main manifestations; ② Mental and psychological symptoms such as depression, anxiety, impatience, fear and timidity, or short-term memory loss and inattention are the main manifestations; ③ The decline in the frequency of interpersonal communication, or the decline in social adaptability such as interpersonal tension are the main manifestations. If any one of the above three items continues to attack for more than 3 months, and the diseases that may lead to the above performance are ruled out by systematic examination, they can be judged as sub-health in physical, psychological and social communication respectively. Clinically, the above three sub-health manifestations often coexist. The main characteristics of sub-health include: ① symptoms reflected by physical and mental discomfort, such as fatigue, weakness and emotional changes. , and its situation is difficult to clear for quite some time; (2) various weak manifestations caused by the decline of organizational structure or physiological function that is not suitable for age; ③ Microecological imbalance; ④ Pre-disease physiological and pathological changes of some diseases. Clinical manifestations are varied, such as fatigue, muscle joint pain, dizziness and headache, palpitation and chest tightness, sleep disorder, loss of appetite, epigastric discomfort, constipation in loose stool, sexual dysfunction, fear of cold and heat, easy to catch a cold, dry eyes and so on. Psychologically, it can be manifested as depression, distraction, impatience, irritability, fear and timidity, memory loss, inattention, listlessness and unresponsiveness. Social communication can be manifested in the following aspects: unable to assume the corresponding social role, difficult to work and study, unable to correctly handle interpersonal and family relationships, and difficult to conduct normal social communication.