After 22 years of illness, Dr. Yang is still in good health, and he can't help but sigh how wise the cardiovascular doctor's choice is.
Strictly speaking, diabetic hypertension is not the name of a disease, it refers to diabetes complicated with hypertension.
Clinically, hypertension is often accompanied by diabetes, and diabetes is often accompanied by hypertension, both of which are called homologous diseases. No matter the cause, influence or harm, diabetes and hypertension are closely related, and they often combine to form diabetic hypertension.
After the diagnosis, Dr. Yang is also prepared to take antihypertensive drugs for a long time. But which drug should I choose? After thinking, Dr. Yang finally chose to take sartan antihypertensive drugs. The sartan drugs are also called ARB drugs, and commonly used drugs include valsartan, losartan, irbesartan, telmisartan and candesartan. There are many kinds of antihypertensive drugs in clinic. Why did Dr. Yang choose sartan antihypertensive drugs? What should I pay attention to when taking sartan antihypertensive drugs? Pharmacist Wang will explain them one by one.
Sartan is often called angiotensin II receptor blocker. Drugs can directly act on angiotensin ⅱ receptor, reduce blood flow resistance, and dilate arteriovenous vessels at the same time, so as to lower blood pressure. These drugs are widely used in clinic because of their small side effects and stable antihypertensive effect.
While seeing the excellent effects of sartan drugs, we should also pay attention to its precautions:
The antihypertensive effect of sartan is closely related to the dose. When taking medicine for the first time, you should choose the low dose of the recommended dose. The best antihypertensive effect can only be achieved after taking sartans for 2~4 weeks. If the drug is taken for more than 1 month, the antihypertensive effect is still not good. You can consider increasing the dose reasonably or combining with other antihypertensive drugs, and don't take it in advance.
The sartans can be used in combination with other drugs. Common drug combinations include: sartan and lol (such as betaloc), sartan and horizon (such as amlodipine), sartan and diuretics (such as hydrochlorothiazide). Combined medication can offset the side effects of component drugs and coordinate blood pressure reduction. Pay special attention, if you want to take diuretics, you must first correct the blood volume, stop taking diuretics or reduce the dosage, and then take sartan to reduce the chance of postural hypotension.
During taking sartan, especially when taking potassium-supplementing drugs or potassium-preserving diuretics at the same time, we should pay attention to the occurrence of hyperkalemia, angioneurotic edema and the first dose of hypotension.
In patients with diabetes complicated with hypertension, taking sartans to control blood pressure can improve insulin resistance, and at the same time, it can effectively improve proteinuria caused by diabetes and delay kidney damage.
In patients with left ventricular hypertrophy and hypertension, taking sartan drugs can effectively reduce cardiac remodeling and reduce the probability of stroke caused by left ventricular hypertrophy.
In patients with carotid atherosclerosis and hypertension, taking sartan can delay the speed of carotid atherosclerosis and effectively reduce the risk of stroke.
Patients with chronic kidney disease complicated with hypertension can effectively improve renal blood flow and proteinuria symptoms by taking sartans. If there is unilateral or bilateral renal artery stenosis, sartan drugs should be used with caution.
Patients with hyperuricemia and gout can reduce uric acid content by taking sartan drugs. Patients with gout can take sartan alone, but the combination of sartan and diuretics is prohibited. Diuretics can increase uric acid and induce gout.
Patients who are intolerant of cough caused by taking Pulitzer are much less likely to cause dry cough than those who take Pulitzer.