Recent studies have found that persistent and excessive stress, anxiety and anger can activate sympathetic adrenal system, hypothalamus-pituitary-adrenal cortex system and pituitary-thyroid system, leading to hypertension, arteriosclerosis, coronary heart disease and cerebrovascular disease. However, persistent and intense helplessness, disappointment, depression, loneliness and depression make parasympathetic nerve and pituitary-adrenal cortex system disorder, resulting in asthma, ulcers, skin diseases and tumors.