Pharmacological action: Diclofenac sodium is a non-steroidal anti-inflammatory and analgesic drug derived from phenylacetic acid, and its mechanism of action is to inhibit the activity of cyclooxygenase, thus blocking the transformation of arachidonic acid into prostaglandin. At the same time, it can promote the combination of arachidonic acid and triglyceride, reduce the concentration of free arachidonic acid in cells and indirectly inhibit the synthesis of leukotrienes.
Diclofenac sodium is one of the most effective non-steroidal anti-inflammatory drugs, and its inhibitory effect on prostaglandin synthesis is stronger than aspirin and indomethacin.
Extended data:
Indications of drugs
1, acute and chronic rheumatoid arthritis, acute and chronic arthritis, acute and chronic ankylosing spondylitis, osteoarthritis.
2, scapulohumeral periarthritis, bursitis, tendonitis, tenosynovitis.
3. Low back pain, sprain, strain and other soft tissue injuries.
4. Acute gout.
5, dysmenorrhea or adnexitis, toothache and postoperative pain.
6. Post-traumatic pain and inflammation, such as sprain and muscle strain;
7, ear, nose and throat serious infectious pain and inflammation (such as tonsillitis, otitis media, sinusitis, etc.). ), anti-infective drugs should also be used.
Baidu Encyclopedia-Diclofenac Sodium Sustained Release Tablets