Health sensor development

With the development of medical technology, the real-time monitoring of personal physiological information and the personalized medical care brought by it have been widely concerned. Electrochemical biosensor is a device that can convert chemical signals into electrical signals. They can be used to monitor specific chemicals and are widely used in wearable medical and other fields.

According to reports, the existing implantable sensors have the problem of repeated mechanical damage between rigid devices and soft tissues due to the large modulus of the material itself. In addition, the implantable device based on two-dimensional plane structure design is difficult to achieve minimally invasive implantation, to form a stable interface with tissues, and to achieve long-term accurate monitoring, thus affecting signal acquisition and biological safety.

Professor Peng Huisheng and Associate Professor Sun Xuemei from the Department of Polymer Science of Fudan University, Professor Yu Hongbo from the School of Life Sciences, Professor Xu Fan from the Department of Aeronautics and Astronautics and other multidisciplinary teams designed a multi-level spiral fiber electrochemical sensor through bionic muscle structure. Mechanical simulation and nano-indentation experiments show that carbon nanotube fibers have lower bending internal stress than traditional implant materials (gold wire, polydimethylsiloxane, etc.). ).), and their bending stiffness is closer to soft tissue than other traditional implant materials. At the same time, the team used an injection method suitable for the one-dimensional structure of optical fiber to accurately implant the optical fiber sensor into the target area. The shape of in vitro fiber is similar to that of animal hair attached to the skin surface.

Subsequent cell experiments and tissue sections show that the optical fiber sensor does not cause inflammatory reaction and scar in animals after injection, and it is well combined with surrounding tissues. The optical fiber sensor has good biocompatibility and biological integration.

This work has opened up a new direction in the field of bioelectronics. Through integrated circuit, Bluetooth and corresponding software, the optical fiber biosensor can collect physiological data remotely and in real time, and the device can work stably in blood vessels for up to 4 weeks. So can the invention of bionic optical fiber sensor really avoid hospitalization? I wish you a bright and prosperous future!