Cerebral oxygen saturation monitoring

At present, cerebral oxygen saturation is mostly detected by embedding catheters in carotid and jugular veins, collecting intracranial blood samples irregularly, and then placing the blood samples in a blood gas analyzer for detection. On the one hand, this invasive detection method has a greater risk of bleeding, because it is arterial intubation, especially for middle-aged and elderly people, if the hemostasis is not in place, it may cause bleeding in the body; On the other hand, invasive blood sampling can only be used to collect data at some time points, and it can not be used as a monitoring means to monitor cerebral oxygen in real time. In fact, studies have shown that real-time monitoring of cerebral blood oxygen status and timely intervention can reduce the probability of stroke during or after operation, and shorten the hospitalization time of patients in intensive care unit and general ward.

with the development of science and technology, optical and photoelectric conversion technologies have been effectively and widely used in various fields. Using near infrared spectroscopy (NIRS), according to the absorption characteristics of hemoglobin in this band, the study of non-invasive detection of brain function and the possibility of realizing optical CT in the future have been carried out in Japan, the United States and Britain, and many achievements have been made. This is a very meaningful attempt to apply advanced photoelectric technology to biomedical engineering research. On the other hand, the business community also uses this technology to introduce corresponding high-tech medical instruments, which are applied to operating rooms (especially open chest surgery with cardiopulmonary bypass), neurosurgery, obstetrics and gynecology, drug efficacy testing, brain function research, middle-aged and elderly medicine and many other aspects.

Previously, there were foreign devices for noninvasive detection of cerebral oxygen saturation using near infrared spectroscopy, but the related products were not allowed to enter China until 215, and the price was very expensive. At the same time, brain oxygen technology developed rapidly in China. A new NIRS device invented by the Department of Biomedical Engineering in Tsinghua University uses SRS to analyze the interaction between near-infrared light and brain tissue with high scattering characteristics, that is, EGOS-6 brain oxygen saturation monitor, which has been applied to anesthesia, newborns, ICU and other important departments.