A4 paper size feel too small, too big and bad on the wall, trouble to give an answer.
I see those signs are generally slightly larger than A3 paper, too small to hang up indeed small family. On the wall is not the reason, and then the big sign as long as the wall is big enough to press up. If you want to find a reason because it is not good on the wall, I think the designated medical institutions do not open, more than this trouble.