lcmsms is liquid chromatography tandem quadrupole mass spectrometer, liquid chromatography tandem mass spectrometer, liquid chromatography mass spectrometer.
lcmsms model is: Waters ACQUITY UPLC I-Class PIUSSCIEX ABTriple Quad4500.
Instrument description and operation procedures are as follows:
1, Use. Mainly used for the quantitative and qualitative analysis of micro or trace organic metabolites; the analysis of organic chemical pollutants, such as food, agricultural safety, pesticide and veterinary drug residues and other determination. It can be used for the detection of veterinary drug residues, leptin, mycotoxins, antibiotics and other illegal additives.
2, the principle of performance: the sample in the liquid chromatography system after the initial separation, through the interface into the mass spectrometry, mass spectrometry to the ion source, mass analyzer and detector as the core, in the mass spectrometry ion source is ionized by the mass spectrometry mass analyzer will be the ion fragments according to the number of mass separation, through the detector to get the mass spectral picture. Through the analysis of the compound ion mass-to-charge ratio of the compounds contained in the sample to achieve qualitative and quantitative ESI, APCI ionization source, the mass range m/z: 5~2000 amu.
3, operation: prepare samples of a liquid-mass tuning that is the detection of various parameters of the instrument, such as up to the standard, the tuning passes - tuning through the preparation of the UPLC (preparation of the mobile phase containing volatile acids, bases or salts; exhaust; exhaust), the UPLC (preparation of mobile phase containing volatile acids, bases or salts; exhaust). Salt; exhaust; editing parameters: balanced column) -Edit Q00 parameters (select the working mode of the triple four-stage rod, scanning range, the capillary outlet fracture voltage and other parameters) -Save the collection method, enter the sample information, a sample testing a qualitative analysis software to view the data a data processing, print the report