China's first GMP comprehensive water service provider - net Derui for you to answer:
The cleaning procedures of the equipment should be guided by the following principles:
1, there is a clear washing method and washing cycle.
2, clear key equipment cleaning verification methods.
3, the cleaning process and post-cleaning inspection of the relevant data should be recorded and saved.
4, the cleaning of aseptic equipment, especially the parts and components in direct contact with drugs must be sterilized, and marked with the date of sterilization, microbiological validation, if necessary. Sterilized equipment should be used within three days.
5. Certain movable equipment may be moved to the cleaning area for cleaning, disinfection and sterilization.
6, the same equipment for continuous processing of the same aseptic products, between each batch to be cleaned and sterilized; the same equipment for processing the same non-sterile products, at least weekly or after each production of three batches of comprehensive cleaning.