The punishment basis for operating Class II and Class III medical devices without a license is Article 81 of the Regulations on the Supervision and Administration of Medical Devices. The main content is that if a unit engages in the business activities of third-class medical devices without permission, the relevant departments will confiscate the illegal income, medical devices illegally produced and operated, and tools, equipment, raw materials and other items used for illegal production and operation; Impose a fine according to the value of medical devices illegally produced and operated; If the circumstances are serious, it shall be ordered to stop production and business.