1, industry chain analysis: the midstream market still has more space
Molecular diagnostics industry upstream for biochemical raw materials and some refined chemicals, etc., which the main diagnostic enzymes, primers and probes, etc., the market is dominated by foreign brands, on behalf of Roche, Meridian life science, Solulink, etc., and the domestic market is almost blank.
Molecular diagnostic industry in the midstream for the production of molecular diagnostic instruments and reagents, molecular diagnostic instruments are divided into high-end and mid-range, high-end products are mainly gene sequencer, the market is basically monopolized by foreign countries, the domestic only Huada Zhizao have products in mass production, mid-range instruments have nucleic acid extractor, PCR amplifier, etc., the market has basically realized the domestic substitution; most of the reagent kits have been realized domestically.
Industry downstream is mainly medical institutions, such as hospitals, third-party medical testing services, research institutions, laboratories, etc. are involved in molecular diagnostics, mainly low-end, high-end molecular diagnostics less, there is a larger space for development in the country.
2, upstream: raw material enzyme industry to accelerate the localization
Raw material enzyme is a molecular diagnostic reagent raw materials, the most core components, determines the accuracy of the results of the molecular diagnostics, long-term monopoly by foreign enterprises. Raw material enzymes are mainly used in the probe method, gene sequencing, isothermal amplification, molecular hybridization, according to different functions can be divided into polymerase, reverse transcriptase, sequencing enzyme, etc., in the PCR, second generation sequencing and other molecular diagnostic techniques play an important role.
The huge testing demand brought by the new crown epidemic has driven the sales of upstream molecular diagnostic reagent raw material enzymes to surge. China's molecular diagnostic raw material enzyme market size grew from 1.4 billion yuan in 2016 to 3.2 billion yuan in 2020, with a CAGR of 23.0%, and preliminary statistics in 2022, China's molecular testing raw material enzyme market size will reach 3.4 billion yuan.
The main drivers of China's molecular diagnostic raw material enzyme market to maintain high growth are: 1) molecular diagnostic penetration rate after the new crown epidemic, testing organizations and residents continue to increase demand for testing; 2) China's molecular diagnostic market and molecular diagnostic reagents for scientific research market is developing rapidly, continue to drive the development of molecular diagnostic enzyme raw material industry; 3) national policy to encourage and pay attention to the key raw materials of molecular diagnostic reagent Independent and controllable, raw material enzyme industry localization accelerated.
3, midstream: broad prospects for domestic substitution
The in vitro diagnostic overall domestic accounted for about 40%, but the subsectors are at different stages of development, the difference between the localization is obvious, which the molecular diagnostics market in the in vitro diagnostic industry in the domestic rate is low, but the fastest rate of domestic substitution, the prospects for domestic substitution is broad.
From the point of view of the sub-product market, the current high-end molecular diagnostic instrument market is basically monopolized by foreign countries, the mid-range instrument has basically realized the domestic substitution; most of the reagent kits have also been localized, specifically as follows:
More research and analysis of this industry is detailed in the Juniper Research Institute of the Chinese molecular diagnostics industry, "China molecular diagnostic industry market outlook and investment strategy planning analysis report".