Analysis of causes of high total protein

Question 1: What is the reason for high total protein? The reasons for high total protein are analyzed as follows: the resulting decrease in the white/globule ratio cannot be considered as worsening of liver function. If the total protein is higher than 35 g/L, it indicates poor liver function and insufficient reserve capacity, which is a sign of worsening liver function. 1. Total protein is composed of two parts, albumin and globulin. Under normal circumstances, albumin and globulin fluctuate within the normal range. Total protein also maintains a certain value range, and albumin and globulin maintain a certain ratio. , but in disease states, due to changes in the contents of albumin and globulin, the white/globulin ratio and total protein content also change accordingly. In chronic viral hepatitis, the persistence of the virus leads to the proliferation of the immune system and the continued increase in globulin. If the liver function is still relatively good at this time and can synthesize a sufficient amount of albumin, the test results at this time are often Albumin is normal, globulin increases, and total protein also increases. The white/globule ratio can be normal or slightly decreased. The formula is: T=A+G (total protein=globulin+albumin)

In In the early stage of chronic hepatitis, when the liver function is still good, that is, the increase in globulin is manifested, the formula is: T↑=A+G↑

When the liver disease further develops to the late stage, or when cirrhosis occurs, due to Liver function deteriorates, the ability to synthesize albumin decreases, albumin begins to decrease, globulin further increases, albumin/globulin further decreases, total protein can be normal or increased, expressed in the formula: T=A↓+G↑ A/ G↓ 2. Analysis of the reasons for high total protein. The reasons for high total protein mainly include the following two aspects: Reasons for high total protein 1. Physiological increase: High total protein can also be caused after strenuous exercise. Reasons for high total protein 2. It is caused by certain causes. Common reasons are: 1. Autoimmune diseases 2. M-globulinemia: such as multiple myeloma, lymphoma, primary macrolobulin Globulinemia, etc. 3. Chronic liver diseases: including autoimmune chronic hepatitis, chronic active hepatitis, cirrhosis, chronic alcoholic liver disease, primary juice cirrhosis, etc.; high levels of globulin are related to the severity of liver disease . 4. Chronic inflammation and chronic infection: such as tuberculosis, malaria, etc. Based on the above analysis of the reasons for high total protein, it should be pointed out that although albumin and globulin are both important proteins in the blood, albumin is more closely related to the functional status of the liver, and it mainly reflects the synthetic ability of the liver. If the albumin can still remain normal, it means that the liver function still has a certain reserve capacity. At this time, even if the globulin increases and the white/globule ratio decreases, it cannot be considered as a deterioration of the liver function. If the albumin drops significantly, below 35 g/L, it indicates poor liver function and insufficient reserve capacity, which is a sign of worsening liver function. Some people think that any decrease in white blood cells is a symptom of liver cirrhosis. This is obviously a misunderstanding, because if the decrease in white blood cells is caused by an increase in globulin, it can only indicate the proliferation of the immune system, but not the deterioration of liver function, which is not serious. Signs of liver disease or cirrhosis. Hepatology experts remind: Although an abnormal white/globule ratio does not indicate deterioration of liver function, the cause of high total protein may be a precursor to severe hepatitis. Therefore, when the cause of high total protein cannot be clearly understood, patients should You must not take this lightly and go to the hospital for treatment as soon as possible. Correct treatment under the guidance of a doctor can prevent the disease from developing further and evolving into chronic hepatitis.

Question 2: Why is the total protein high? According to experts, total protein (TP in English) is a common indicator in liver function tests. The total protein content can be used to diagnose liver diseases. In clinical examination, many people have high total protein. So what is the reason for high total protein? What causes total protein to be high? Experts said that there are many reasons for high total protein, which should be analyzed based on the specific condition. Generally, there are two situations of physiological increase and pathological increase in total protein high score. What causes high total protein? 1. Physiologically high total protein. Physiologically high total protein is mostly caused by strenuous exercise, excessive drinking, and poor rest. 2. Pathological high total protein Pathological high total protein is clinically common in the following diseases: Recommended reading >> The difference between hepatitis B halves and HBV-DNA 1. Chronic liver diseases, including autoimmune chronic hepatitis and chronic active hepatitis , liver cirrhosis (liver, chronic alcoholic liver disease, primary biliary cirrhosis (liver, etc.).

: What is the normal value of total protein in liver function? 2. Chronic inflammation and chronic infection: such as tuberculosis, malaria, etc. 3. M-globulinemia: such as multiple myeloma, lymphoma, primary macroglobulinemia, etc. 4. Acute water loss causes blood concentration (such as vomiting, diarrhea, etc.). 5. Multiple myeloma. Friendly reminder from the experts of our hospital: Some of the contents on this website are for reference only. They are intended to provide you with relevant disease knowledge and help you better and more comprehensively understand relevant disease knowledge. They are not used as a basis for disease diagnosis and treatment; if you or your If your relatives or friends have related or suspected diseases, it is recommended that you go to a professional hospital and experts will answer your relevant questions and make the most professional treatment plan according to your condition.

Question 3: Reasons for the increase in total protein Effects of drugs 1. Elevate epinephrine and angiotensin, which have hemoconcentrating effects, leading to an increase in total serum protein. Corticotropin, corticosteroids, synthetic steroids, androgens, growth hormone, insulin, thyroid preparations, and progesterone can promote or increase protein synthesis. Intravenous injection of amino acids can cause an increase in the measurement results. Dexglucoside in the serum produces turbidity during the biuret reaction, causing a false increase in the results, and the mechanism by which Clofibrin causes an increase in total protein is unknown. 2. Reduce anti-epileptic drugs by about 3%. Pyrazinamide, rifampicin, benzene, carbon tetrachloride, and carbon disulfide can damage the liver and reduce protein synthesis. Trimethyldione causes protein loss in urine, and mercury compounds cause albuminuria, both of which can lead to a decrease in total protein. Ammonium ions affect the color reaction and falsely reduce the total protein. Total protein is composed of albumin and globulin. The normal value of total protein is different at different ages: the total protein of newborns is 46~70g/L, and the total protein of infants 7 months to 1 year old is 51~ 73g/L, the total protein for those over 3 years old is 60-76g/L, the total protein for adult men is 68-82g/L, and the total protein for adult women is 67-81g/L. The total protein in the examination may be physiologically elevated or pathologically elevated. Recent strenuous exercise, heavy drinking, or lack of rest may cause a temporary increase in albumin. If you check again after a period of recovery, the albumin will return to normal. Many diseases can cause high total protein, such as vomiting, diarrhea, etc., which cause the water in the serum to decrease. Myeloma, lymphoma, or macroglobulinemia, etc. can cause the increase in globulin, leading to high total protein, acute and chronic liver diseases, and Some chronic infectious diseases can also cause high total protein. Reasons for high total protein The specific reasons for high total protein are as follows: 1. Elevated globulin: Globulin reflects the synthetic function of the liver. In acute hepatitis, the change in globulin is not obvious. In chronic hepatitis, cirrhosis, and liver cancer, the globulin changes. The protein will increase significantly. If its value exceeds the normal value of globulin, it means liver cell damage and decreased liver function. 2. High total protein caused by diseases: such as chronic liver diseases: including chronic active hepatitis, cirrhosis, chronic alcoholic liver disease, primary biliary cirrhosis, etc. Globulin is seriously increased, and globulin is closely related to total protein. It also increases accordingly. 3. Physiological increase: Due to strenuous exercise or high-intensity physical labor, physical overexpenditure, total protein is high. The dangers of high total protein. The total protein test is a test that mainly detects the metabolic capacity of liver function and reflects the reserve capacity of the liver. High total protein will bring certain harm to people. Serum proteins are the most abundant substance in the solid components of serum. When the water in the serum decreases, the concentration of total protein increases relatively, and a high degree of dehydration leads to blood concentration. The harm of high total protein will cause diarrhea, vomiting, shock, high fever, profuse sweating, etc., as well as multiple bone marrow. Tumors, macroglobulinemia, etc. can also show increased total protein. Reasons for low total protein: 1. Hepatocytes are damaged, liver function is impaired, protein synthesis in the liver is reduced, and albumin drops significantly, resulting in low total protein. Usually caused by hepatitis. 2. Protein loss, such as severe large-area burns, massive plasma exudation, and massive bleeding; in nephrotic syndrome, protein in urine is lost for a long time; in ulcerative colitis, a certain amount of protein can be excreted with the feces. 3. Malnutrition or increased consumption, such as long-term insufficient protein content in food or malabsorption caused by chronic intestinal diseases, chronic wasting diseases such as tuberculosis, malignant tumors, cirrhosis, etc. 4. Intestinal diseases: intestinal malabsorption disease, enteropathy, celiac syndrome. 5. Kidney disease, nephrotic syndrome, lipoid nephropathy, glomerulonephritis. What to do if the total protein is too high Generally, the total protein of a normal person is between 60-80g/L. If it exceeds this range, it means that the liver has been damaged to some extent.

If it is chronic liver disease, including autoimmune chronic hepatitis, chronic active hepatitis, liver cirrhosis (liver, chronic alcoholic liver disease, primary biliary cirrhosis (liver) and high total protein, it should also be combined with transaminase and viral DNA Comprehensive analysis of laboratory tests. If it is caused by general non-pathological reasons, patients should pay attention to eating a light diet, rich and reasonable nutrition, insist on physical exercise, consume excess fat and calories, drink appropriate water, pay attention to rest, and avoid exertion. If it is pathological, etc. If it is caused by sexual factors, the patient must go to a professional liver disease hospital for examination in time. If it is caused by hepatitis B, antiviral treatment must be carried out in time to avoid the disease... >>

Question 4: What is the reason for high total protein? In order to answer the question about high total protein, this website specially invited authoritative liver disease experts from Jiangsu Nanwu Liver Disease Research Institute, the best liver disease hospital in Nanjing, to answer this question for patients. Hepatology experts analyzed the following: Reasons for high total protein: 1. Physiological increase: high total protein is also caused by strenuous exercise, excessive drinking, and poor rest. 2. Reasons for high total protein. High is caused by certain causes. Common reasons for high total protein include the following: 1. Chronic liver disease: including autoimmune chronic hepatitis, chronic active hepatitis, liver normalization, and chronic alcoholic liver disease. , primary biliary cirrhosis, etc.; high levels of globulin are related to the severity of liver disease 2. Chronic inflammation and chronic infection: such as tuberculosis, malaria, etc. 3. M-globulinemia: such as multiple myeloma, lymphoma. Tumors, primary macroglobulinemia, etc. The normal value of albumin is 4. The water in the serum decreases, causing the total protein concentration to relatively increase. It is common in hemoconcentration caused by acute water loss (such as vomiting, diarrhea, etc.); in shock, capillaries Blood vessel permeability changes and plasma is concentrated; in patients with chronic adrenocortical insufficiency, plasma is also concentrated due to loss of sodium and secondary water loss. 5. Increased serum protein synthesis (mainly increased globulin). More than 100g/L, more common in patients with multiple myeloma. Warm reminder: The Liver Disease Treatment Center of Jiangsu Nanwu Liver Disease Institute specially invited by this website is a first-class comprehensive hospital, which has achieved very good treatment in the treatment of liver diseases and is authoritative in liver diseases. Experts treat patients, and tens of thousands of liver disease patients have recovered; in the treatment of liver disease, the best method used by Jiangsu Nanwu Liver Disease Institute is anti-HBV three-oxygen autologous blood transfusion therapy, and anti-HBV three-oxygen autologous blood transfusion therapy. The treatment is unique, safe, has no toxic side effects, does not rebound, is not durable, and has a high transfer rate. It is the preferred treatment method for patients.

Question 5: What is the reason for high total protein? It depends on your daily food intake. It’s not about too much meat or eggs. If not, you need to check for absorption problems from time to time

Question 6: Why is the serum total protein high when liver function is abnormal? As an indicator in liver function tests, serum total protein The normal range of protein is between 60 and 80g/L. Serum total protein is mainly composed of albumin and protein. When some patients have abnormal liver function, the test results will show high serum total protein. It is recommended that patients must Under the doctor's advice, further examination or systemic treatment is carried out in order to control the onset of the disease in a timely manner and allow the liver function to return to normal as soon as possible. Generally speaking, the reasons for high serum total protein during liver function tests can be attributed to two points. One is pathological reasons, and the other is physiological reasons. The details are as follows. 1. Pathological reasons: High serum total protein during liver function tests is common in patients with chronic hepatitis, cirrhosis, and liver cancer; high total protein in liver function tests reduces the water in the serum, causing the total protein concentration to increase; in addition, chronic Inflammation or infection, such as tuberculosis, malaria, multiple myeloma, macroglobulinemia and other diseases can also cause high total protein. 2. Physiological reasons: Physiological reasons for high serum total protein during liver function tests mainly include malnutrition, heavy drinking, irregular work and rest, frequent eating of greasy food, etc. At this time, you should pay attention to adjusting your diet, work and rest. and other habits. In general, there are many reasons for high serum total protein during liver function tests. Therefore, when serum total protein is high, you must go to a professional and regular center for a detailed examination to see what is causing it. If the total protein is high, diagnosis and treatment will be conducted based on the cause.

(What are the symptoms of liver function impairment in hepatitis B patients) Hunan Armed Police Corps Hospital is the best liver disease treatment hospital in Hunan Province. It has a number of liver disease treatment technologies and various advanced medical equipment. Many well-known domestic liver disease experts are involved in liver disease examination and He has rich clinical experience in diagnosis and treatment. He can provide scientific diagnosis and treatment based on the specific reasons for high serum total protein, which has helped many patients with liver disease improve.

Question 7: Why is the total protein high in the liver function test results? The liver is involved in the metabolism of the body's substances. Therefore, liver dysfunction will cause hyperalbuminemia, but high serum protein is not necessarily related to the liver. ――By the way, you can ask the doctor directly after the test