Automatic biochemical analyzer (ACA for short): Biochemical analyzer: an instrument used for detecting and analyzing vital chemicals, providing information basis for clinical diagnosis, treatment and prognosis of diseases and health status.
Optical system: is the key part of ACA. The old ACA system uses tungsten halogen lamps, lenses, color filters, and photocell components. The optical part of the new style ACA system has been greatly improved, the ACA spectroscopy system has a front spectroscopy and a back spectroscopy due to its different light positions. The advanced optical components use a set of lenses between the light source and the colorimetric cup, which will turn the light projected by the original light source lamp into a beam of light speed through the colorimetric cup (this is different from the traditional deeded beams) so that even if the colorimetric cup is small enough, the point beam can pass through it. This saves reagent consumption by 40-60% compared to conventional methods. After the spot beam passes through the colorimetric cup, the spot beam is reduced to the original beam by a set of reduction lenses (wide-aberration correction system) and divided into a fixed number of wavelengths (about 10 or more wavelengths) by a grating. The optical/digital signal direct conversion technology is used to turn the optical signals in the optical path directly into digital signals. The electromagnetic wave interference on the signal and signal transmission process of attenuation is completely eliminated. At the same time, the use of optical fiber in the signal transmission process, so that the signal to achieve no attenuation, the test precision increased by nearly 100 times. The closed combination of optical path system also makes the optical path without any maintenance, and accurate spectroscopy, long life.
Constant temperature system: Because of the great influence of temperature on the reaction results of biochemical reactions, the sensitivity and accuracy of the constant temperature system directly affect the measurement results. Early biochemical instruments use air bath method, and later developed to set the dry air bath and water bath advantages in one of the thermostatic liquid circulation indirect heating dry bath. The principle is to design a thermostatic bath around the colorimetric cup, and add a kind of odorless, non-polluting, non-evaporating, non-deteriorating stable thermostatic liquid in the bath, which has a large capacity, good thermal stability and uniformity. In the colorimetric cup does not directly contact the thermostatic liquid, overcoming the water bath thermostatic easy to be contaminated and air bath is not uniform, unstable characteristics.
Sample reaction stirring technology and probe technology: the traditional reaction stirring technology using magnetic beads and vortex stirring type two. Nowadays, the popular stirring technology is a stirring unit consisting of multiple sets of stirring bars that mimic the manual cleaning process. While the first set of stirring bars is stirring the sample/reagent or mixed solution, the second set of stirring bars simultaneously performs high-speed and efficient cleaning, and the third set of stirring bars also performs the warm-water cleaning and air-drying process at the same time. In the design of individual stirring rods, a new spiral type high-speed rotary stirring is used, the direction of rotation is opposite to the spiral direction, which increases the strength of stirring, and the stirred solution does not foam and reduces the scattering of light by microbubbles. Reagent and sample probe in accordance with the principle of early capacitive sensing, but slightly improved to increase the blood clot and protein clot alarm, in accordance with the alarm level of the re-test results, reduce the sampling error, improve the reliability of the test results. The number of large biochemical instruments tested per hour is more than 1000, so automatic retesting is quite important, the subjective evaluation of test results and manual retesting can not meet the clinical needs.
Other aspects: reagents, samples, bar code identification and computer registration, early biochemical equipment due to the lack of bar code identification function, the chance of error is more. In recent years, regardless of imported and domestic biochemical instruments are used barcode detection, the use of this technology in biochemical instruments to the development of high-speed ACA provides technical support, but also makes the instrument is quite supportive. The development of software is simple and easy, therefore, the barcode detection is the basis of instrument intelligence. Open reagent, as an important factor for hospitals to choose models, whether the instrument supports open reagent is very important. After the reagents are open, hospitals and research units can independently choose the reagent supplier, and have greater freedom in measuring the price, the reliability of the results of the low-degree instrument, and the validity period of the reagents. Ion Selective Electrode Analysis Accessory (ISE), human serum and urine electrolyte indicators are quite important, and hospitals can save money when the ACA system comes with ISE.
The automated analyzer is the original manual process of sampling, mixing, temperature bath (37 ℃) testing, results calculation, judgment, display and print results and cleaning and other steps all or part of the automatic operation. Today, biochemical tests are essentially automated analyses, and there are fully automated biochemical analysis systems designed for large or very large clinical laboratories and commercial laboratories, which can be configured arbitrarily according to the laboratory's testing volume.
Whether it is today's fastest running (9600Test/h) modular fully automated biochemical analyzers, or the original manual operation used for colorimetry photoelectric colorimeter, the principle of the use of spectroscopic technology in the absorption spectroscopy. It is the most basic core of biochemistry analyzer. ◆ Leading technology optical reaction system
◆ Highly efficient and worry-free automatic flushing system
◆ Intelligent and sensitive liquid level detection system
◆ Simple and fast software operating system
◆ Timely and considerate nationwide service network:
Testing speed: 300 tests/hour (excluding ion test)
Instrumentation with Power on self-test function, self-test abnormalities, display a fault prompt;
The instrument is operated on a Windows platform, full Chinese system, with a reaction monitoring screen, the operator can always understand the status of the instrument;
Optional mode of work: you can arrange the test in the order of the patient can be arranged according to the order of the test also arrange the test in the order of the project.
Testing method: single and double wavelength method, single and double reagent method are optional.
Analysis mode: absorbance, endpoint method, two-point method, kinetic method, standard curve method, factor method, control tube method;
The instrument is open to the reagents, according to the requirements of different reagents can be set up in advance the project parameters, after the comparison of the accuracy of the deposited into the instrument, for the clinical test call.
The instrument has emergency sample insertion function, and prioritize the arrangement of emergency sample testing;
The instrument has sample pre-dilution function and automatic re-testing function, when the sample test result is ultra-linear, the instrument can be arranged for pre-dilution and re-testing;
The instrument has an indoor quality control function, which can realize real-time monitoring of the test results on the spot;
The instrument has Power failure protection function: after restoring power supply, it can continue to execute the original running program.
The reagent pool has 24-hour uninterrupted low-temperature refrigeration function, and the temperature inside the pool is from 2℃ to 10℃;
The output of the instrument: project parameters, calibration curves, dynamic reaction curves, absorbance, concentration, enzyme activity, judgment results of the normal reference value, as well as the test data of the quality control products and the QC chart.
Sample system
Sample library: 65 sample spaces, can be placed in a variety of original blood collection tubes, test tubes and micro sample cups. And there are two sample trays, which can be exchanged for any use.
Sample volume: 2.5ul～40ul, determined at the time of project preparation, the instrument automatically takes samples in 0.05ul increments.
Sample needle: with automatic liquid level detection and anti-collision safety protection.
Sample needle cleaning: in addition to the special cleaning solution for the internal and external surfaces of the sample needle rinse, but also with warm distilled water rinse the outer surface of the sample needle, hot air blow dry.
Operating System
Software Operating System: Windows XP
Data Processing: Storing and outputting a variety of test data and graphs (including project calculations) with no time or storage limit.
Operating software advantages:
Chinese online help operation guide;
Full open test parameter settings;
Real-time response curve, the whole process of detection;
Simultaneous application of the main and sub-wavelength detection, to eliminate interference, to obtain the most accurate results;
Reagent quality information, the sample analysis results, the system units Real-time diagnosis of the state;
Specific user management password to assign user's operating privileges;
Sample test data editing. A variety of report form styles are available for users to choose from.
Calibration and quality control:
Calibration mode: various calibration modes, single-point, two-point, multi-point (linear regression method, semi-logarithmic method, full logarithmic, quadratic curve, cubic curve, four-parameter method)
Calibration period: set up by yourself at any time according to the user's needs.
QC software: 3 levels of quality control; equipped with L-J quality control chart, westguard, multi-rule, -R and other quality control rules.
Monitor: 17# LCD monitor.
Printing function: Chinese printing content is optional, support remote report card printing.
System interface: RS-232 standard interface. Parameter list