The main hospital of the College of Medicine is located in the Zhongzheng District of Taipei City, divided into two sites, east and west, separated by Zhongshan South Road.
The west site, which follows the original site during the Japanese rule period, is located at No. 1, Changde Street, and is the only door plate on Changde Street. It is mainly responsible for outpatient services. At the same time, the wards of the Department of Psychiatry, the Department of Rehabilitation, the Department of Medical Oncology, and the Department of Dentistry were all located in the West Site, and after the SARS outbreak in 2003, the 6E1 Negative Pressure Isolation Intensive Care Unit was added. In addition to the main building, the West site has a Laboratory Building in the southwest and a Children's Medical Building (not yet operational) in the northeast.
The east site is 7 Zhongshan South Road, the original site of the medical school, the building is connected to the medical school building. The East Site building was opened in September 1991, and is mainly responsible for emergency care, hospitalization, surgery and specialized testing programs, in addition to the hospital and medical school building, there is also the Genetic Body Medical Center.