The era of the smart machine Taiwan's machinery industry to show off the R & D capabilities Have you seen the movie "The Countess"? The protagonist Bartoli? The image of Elisabeth with the blood of the skin is y rooted in people's hearts, but also accurately describes the women's pursuit of love, at any cost to preserve the thinking of the face. Thanks to modern technological advances, the hidden secrets of blood platelets can be found in the bloodstream, which can not only help heal wounds, but can also be used for cellular repair, such a miraculous "medical" use, the editor himself does not count, this time with a professional dermatologist Su Chengwei to answer. Clearing up the hidden secrets of blood Modern medicine looks at it this way Human blood is divided into plasma and blood cells, plasma accounted for about 55% of the total blood volume, while the blood cells accounted for about 45%, and blood cells can be divided into red blood cells, white blood cells and platelets, and so on. The president of Chengzhi Dermatology Clinic, Mr. Su Chengwei, said that platelets were discovered more than a hundred years ago, and early scientists believe that as a stopgap, on average, every 7 to 14 days will be metabolized by the spleen, in the last 30 years, research found that platelets are rich in various types of growth factors, when the wound or tissue damage, platelets will release growth factors to start a chain of messaging, so that the cell division to repair the tissue. Intelligent scientists began to study whether platelets had other medical uses, and found that platelets can repair other damaged parts of the skin, blood vessels, and so on. Currently the simplest way to obtain platelets, the blood is put into a centrifuge tube and centrifuged, the blood is centrifuged and divided into three layers, taking the middle weight liquid, which we call platelet-rich plasma (PRP, Platelet-Rich-Pla *** a). The limitations of the application prompted scientists to develop PLT cryopreservation technology The current application of PRP has a history of 30 years, and it can be applied to chronic tendonitis, muscle strains, ligament damage, degenerative arthritis, or post-surgical repair of cruciate ligaments. The technology has also been applied to burn patients to further accelerate wound healing.
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In recent years, German and Japanese scientists have published a study that utilizes freeze-drying technology to concentrate and preserve platelets. Su Chengwei said, scientists will freeze-drying technology applied to PLT, the patient only need a one-time extraction of about 250 cc donor bag of blood, blood by the technical separation, crystallization, this technology is known as PLT freezing crystal technology (Platelet-Lyophilized Treatment), can be stored for a long time, quantitatively each bottle of frozen crystalline PLT quantity, so that the treatment effect can be more constant.
PLT contains a variety of growth factors and is more effective when administered by a physician
Platelet-Lyophilized Treatment (PLT) is the most common form of PRP, and is produced by a patented on-site centrifugal separation process. Single session Preservability Can be stored at room temperature for 3 years Need to be used up on-site Content 1 billion platelets per vial Cannot be measured on-site Applicable to patients who need multiple or long-term treatments Small number of sessions and need to be used up immediatelyPLT contains many types of growth factors. Growth Factor), KGF (Keratin Growth Factor), TGF-Beta, VEGF, and others. At present, the research on the function of growth factors is not yet thorough, and their names just happen to be found in a certain cell. For example, although EGF is the abbreviation of epidermal growth factor, the latest research has found that, for patients with hair fall (male pattern baldness and round baldness), EGF can accelerate resting hair to the anagen phase, and although KGF is the abbreviation of keratin growth factor, the research has found that KGF has the function of protecting the cells of the hair follicle. In addition, TGF-Beta, the latest research has found that it can regulate T-cells (immune cells) and reduce the IgE (Immunoglobulin E) allergy index, thus reducing the body's allergic reactions, for allergic rosacea or liver spots, there are also studies that believe that it will be improved because of the increase in TGF-Beta.
Su Chengwei further explained, in general, where PDGF, FGF, VEGF and other growth factors will start a series of fibroblast proliferation, inducing fibroblasts to generate secretion of collagen and elastin, but with the growth of our age or exposure to the sun and other factors, the number of fibroblasts and the activity of the gradual decrease in the texture of the skin began to be rough, fine lines, the appearance of the The skin texture becomes rough, fine lines develop, and the appearance of ageing is noticeable. These growth factors reactivate fibroblast activity and can help improve the skin's condition. How is PLT applied to the human body?
The best way to use PLT is to have a professional doctor apply it to the affected area. If you apply it externally as a skin care product, you will get a better result, but in reality, the growth factors are not absorbed by the skin and go into the dermis.
So the external application in the minimally invasive wound, the theory can increase the absorption, such as shuttle lasers, skin purification lasers or picosecond lasers. Su Chengwei reminded, PLT frozen crystal technology to solve the traditional PRP can not be saved and the concentration of the problem of instability, but the production time is longer and more expensive, clinically more suitable for the need for a number of times and the economy is more affordable patients.
Images courtesy of imdb-The Countess (2009) Photo Gallery, Seiji Dermatology Clinic
Topics: PLT, PRP, Wound Healing, Cruciate Ligament Surgery, The Countess, Chronic Tendonitis, Seiji Dermatology Clinic, Growth Factors, Baldness, Cellular Repair, Fiber Matrix Cells, Cosmetic, Hair Loss, Seung-Wai So, Platelets, Blood, Degenerative Arthritis