The meaning of CR, PR, SD, PD, MR, and NE in the evaluation of tumor efficacy (the definitions are constantly being updated, MR is no longer commonly used)
PD, progressive disease ) The product of the maximum diameter of target lesions increases by at least ≥25%, or new lesions appear
Stable disease (SD, stable disease) The sum of the maximum diameters of target lesions decreases to less than PR, or increases to less than PD.
Partial response (PR, partial response) is when the product of the maximum diameter of the target tumor and its maximum vertical diameter is reduced by more than 50% and maintained for more than 4 weeks.
Complete response (CR, complete response): all target lesions disappear, no new lesions appear, and tumor markers are normal, maintained for at least 4 weeks
MR: minimal response, improvement, very weak With the efficacy of the drug, the tumor shrinks between 25% and 50%.
NE: Not Evaluated, not estimated, unable to be evaluated.
There are two efficacy evaluation standards, namely WHO and RECIST
-WHO (based on the change in the product of the two largest vertical diameters) =RECIST (based on the sum of the two longest diameters) Based on changes)
CR -WHO all lesions disappeared for 4 weeks = RECIST all lesions disappeared for 4 weeks
PR -WHO reduced by 50% maintained for 4 weeks = RECIST reduced by 30% maintained 4 weeks
PD-WHO increased by 25% = RECIST increased by 20%
Not CR/PR/SD before the lesions increased. Non-CR/PR/SD before the lesions increased
< p>SD -WHO non-PR/PD =RECIST non-PR/PD