This medicine is mainly active immune cells, with tens of thousands, which are packed in infusion bags and injected into patients at one time. Two months later, the active immune cells killed the cancer cells in the patient's body and achieved zero clearance, thus achieving the effect of treating cancer.
In the video, the professor said this. In order to make non-professionals understand, he made an analogy to describe the principle of treating this cancer disease and eliminate cancer cells from the root.
He said, for example, the human body is nature, cancer cells are wolves, and hunting dogs are active immune cells, killing wolves. Wolves are very effective. A dog can't beat a wolf. Seven or eight dogs will attack a wolf at the same time, or more dogs will deal with a wolf until the dogs kill all the wolves. What should we do to achieve this goal? Let dogs clone quickly, one dog becomes ten dogs, ten dogs become 100 dogs, and the number of wolves remains unchanged. Then use ten times as many dogs to deal with a wolf, and finally kill all the wolves in nature, thus eliminating the extremely harmful animal species.
This medicine uses cloning technology to quickly replicate an active immune cell that is conducive to killing cancer cells in the body, so that cancer cells can be eliminated within two months, thus achieving the purpose of treating cancer.
It is mentioned in the video that this drug is only suitable for the treatment of some malignant tumors and has limitations, not all cancers. In other words, not all cancers can be effective in one shot, reaching the goal of 100% cancer treatment.
Let's talk about 1.2 million anticancer drugs first. Why can't they be sold at 100 yuan each?
In the process of research and invention of high-tech products, the state should invest a lot of manpower and financial resources, consume a lot of time and energy of scientists and burn brain cells. The selection and preparation of instruments, equipment and materials need to be refined and carefully calculated, which is beyond our understanding.
In a word, science and technology are productive forces, and the products cloned by high technology are priceless, costly and value for money. The manufacturing cost of 65438+200,000 thousand needles injection is not the cost of 100 yuan. Don't ask these unrealistic questions on a whim. Think of a cold, headache and brain fever. 100 yuan is difficult to cure, not to mention the cancer with extremely high mortality and the most difficult treatment. /kloc-how to cure 0/00 yuan?
At present, this drug for treating cancer is only in the experimental stage, and whether cancer cells will recur in the later stage is still in the experimental stage. No one can be sure that cancer will be cured after this injection. On the surface, the elimination of cancer cell data does not mean that cancer cells will not recur. If cancer cells are in suspended animation, will they be resurrected? This requires further research and discussion by scientists.
A new expensive injection for treating cancer,1.2000 needles, is like the price of diamonds (astronomical figure of1.2000), while the price of 1.000 yuan is like the price of soil. Once upon a time, the price of diamonds would fall to the price of soil.
At present, CAR-T cell therapy is a new type of immunotherapy. Also known as immunotherapy of chimeric antigen receptor T cells. As we all know, T cells are an important force in the body's own immune system, which can eliminate cancer cells in the body. CAR-T cell therapy is to add CAR receptor to somatic cells in patients.
The therapeutic principle of CAR-T cell therapy, 1, separates immune T cells from patients, adds a tumor recognition cell to T cells through genetic engineering, and activates chimeric antibodies of T cells to kill tumor cells, thus having the ability to automatically recognize cancer cells. Once cancer cells are found, they will launch suicide attacks and die together. 2. In vitro culture, a large number of CAR-T cells were expanded. Generally speaking, a patient needs billions to billions of CAR-T cells. The amplified CAR-T cells were infused into human body. Under the close monitoring, the patient did not have any violent reaction, and the treatment was over.
20 12 An American hospital took the lead in treating a 7-year-old girl with CAR-T, and it was relieved. Since then, the clinical research on CAR-T in the United States and China has reached 100 respectively. Since 20 16 in China, CAR-T has not only treated leukemia, myeloma and lymphoma, but also provided new ideas and strategies for solid tumors, such as pancreatic cancer and liver cancer.
In 20021year, the State Administration of Pharmaceutical Products successively approved Roche's new tumor immunity drugs, atilizumab, Taishengqi, sevotinib tablets (Vorisha) and tillizumab (Baizeran), for the treatment of non-small cell lung cancer. These biological immune drugs have brought good news to lung cancer patients.
On June 22nd, 20021,the State Pharmaceutical Product Supervision Administration approved the listing of CAR-T drug developed by Fosun Kaite Biotechnology Co., Ltd., a Sino-US joint venture of Fosun Pharma, which provided a new choice for refractory large B-cell tumors.
Because CAR-T is a cellular immunotherapy with gene editing technology, the process quality is extremely high and it cannot be mass-produced. The domestic market price of similar Aquilencel injection is 6.5438+0.2 million yuan. This is much less than the foreign pricing of $350,000 to $500,000, but it still puts ordinary people at risk. With the improvement of preparation technology, or many domestic enterprises can put into production, the drug price will be accepted by the people.
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An anticancer drug injection can buy 6.5438+0.2 million yuan, and there is still a market, which shows that it is worth it. And why can't it sell 100 yuan, which shows that 100 yuan is not worthy of its market value.
There are many factors that determine the price of commodities, but the most important ones are two aspects: one is the production cost of commodities, and the other is the market supply and demand of commodities. The cost of goods includes not only the price of raw materials and the production consumption of workers, but also the cost of research and development. This new anticancer drug injection must be the result of years of research and development, and the research and development cost is very high. In addition, the production process is complex, raw materials are scarce, and the price is definitely high. However, due to the current small output, product shortage and large market demand, this relationship between supply and demand also determines that the price will definitely be high.
Perhaps, with the further development of science and technology in the future, the research and development cost of drugs will be reduced, the production cost will be reduced, and the market price will be reduced to a certain extent. However, it should be impossible to buy a product with 100 yuan for 1.2 million yuan.
For example, in the 1980s, our monthly salary was about 100 yuan, while the price in Pu Sang was about180,000 yuan. Now, with the progress of the automobile industry, the price of family cars has been continuously lowered under the condition that wages have increased by dozens of times. The price of Santana is positioned below100000 yuan. This adjustment range is the result of the joint action of production progress and market regulation. However, if you want to buy a car with 100 yuan, it is impossible.
The above is my personal opinion, welcome friends to exchange guidance. Thank you!
Good question! Good question! I think the general public wants to know this question, especially our grassroots people urgently need to know this question, so I won't beat around the bush and directly answer the question that everyone needs to know: 1.2 million anticancer drugs are useful? Why can't you sell 100 yuan each? Let's talk it over. My answer is based on facts and reasoning. I hope that according to the examples that have happened around me, it will inspire and help you to discuss the topic.
The research on cancer cells is not new in the medical field. Since the discovery of cancer, we humans have launched scientific research and psychological preparation against cancer. In scientific research and medical colleges all over the world, we have invested a lot of energy, manpower, material resources and personnel in the research of cancer cells, and the financial resources spent every year are incalculable! So far, the treatment of cancer is still difficult to completely kill all cancer cells, and many problems remain to be solved. Therefore, every time a new technology is studied, a new drug needs to invest a lot of money and manpower, which is not what most people think. As far as I know, every new drug and technology for treating cancer must first have powerful new medical resources and the participation of scientific and medical professionals who understand cancer research. Moreover, there must be necessary professional instruments. It is said that some scientific research instruments cost millions. The new drugs developed by the company need several years of clinical trials, and the successful trials must be reported to the relevant administrative departments for approval, and some still need to apply for world patents or domestic patents. Without the corresponding new drug list, it is impossible to enter the market, so it is reasonable that we ordinary people can't afford drugs to treat cancer.
So 1.2 million anticancer drugs are useful? The answer is: all drugs approved by National Medical Products Administration and the health department, whether it is10.2 million or 10.8 million, are effective. Why can't I sell 100 a piece? This is really because it has invested too much in scientific research. If so, scientific research institutions will face the risk of being shut down, because they can't afford to move businesses, and it is reasonable that they can't sell 100 each.
Ordinary people can't afford expensive anticancer drugs. We can only hope that the national economy will remain strong. Only when the country becomes rich and reaches a certain economic capacity, maybe the country will help us solve these problems. Of course, there are still many problems that the government has to solve, and they are also very urgent at present. We believe that one day all of us can afford this expensive cancer drug.
1.2 million anticancer drug effective? The answer is of course it works. Not to mention1200,000 anticancer drugs, even100,000 anticancer drugs have certain anticancer effects. One of my relatives used 10 1000 bottles of anti-liver cancer drugs and laser treatment, which effectively treated cancer. Now the cancer bag has not spread and developed, and he is still alive in his eighties this year. Not all cancers can't be cured. As long as they are treated properly, there is still great hope.
Express: May our country be stronger! May we ordinary people can afford this expensive anticancer drug!
Good, good, good. Science and technology are the primary productive forces, and finally anti-cancer drugs have been developed.
Since the country has approved the import of treatment, it shows that this medicine is safe and effective. That is, 1.2 million is expensive, which is not expensive for the rich. 1.2000 is it expensive to buy a life? No amount of money can be brought into the coffin.
Everyone knows that capital is profit-seeking, and people spend a lot of money on research. Perhaps the cost of an injection of medicine may be only one yuan, and the scientific research funds of others may cost 99,999 yuan to add to a dose of medicine. Besides, people are monopolizing technology, so you want to buy one for 100. Do you think American imperialists are philanthropists?
It's not impossible to buy a hundred dollars. You have to wait slowly. There's nothing you can do if you can't afford it. Just like coronary heart disease, it turned out to be incurable. But heart bypass surgery is simple. When this technology was first introduced to China, many people could not afford it, and medical insurance was not reimbursed. Only the rich can do it. Gradually, the technology has matured, the cost of surgery has come down, ordinary people can do it, and the medical insurance for surgery has also been reimbursed.
This is also the contribution of the rich, taking the lead in testing drugs. Moreover, capitalists will be willing to lower the price if they pay expensive surgery fees and earn a lot of money.
Therefore, ordinary cancer patients need to wait slowly, but if they want to drop to 10 1 year, cancer is not a cold.
Do you have any cheap anticancer drugs? Have you seen the movie "Survival Desire"? Gleevec, which is mentioned in it, has been mass-produced and is still so expensive. A box of medicine costs tens of thousands of yuan, and it won't take long to finish it. After several courses of treatment, hundreds of thousands of yuan will be gone, and this medicine can't cure the disease, it can only inhibit the development of the disease, that is, taking it for 10 thousand years.
Anticancer drugs are expensive because of high research and development costs. Whether an anticancer drug with a price of10.2 million yuan is useful is uncertain, because too few people use it. But judging from the aunt who received the injection, it seems to be really effective and can be used to save lives.
Similar anticancer drugs are expensive not because of the high manufacturing cost, but because of the amazing research and development cost.
The biggest cost of any pharmaceutical company, especially high-end pharmaceutical companies, is research and development expenses. The annual R&D expenditure is astronomical, which can account for a large part of the income. The drugs developed need to bear high research and development costs.
For example, to develop a new anticancer drug, the initial investment is 20 billion yuan, and the manufacturing cost of each box is 1 1,000 yuan. So you can earn 500 yuan by selling a box of 1500 yuan? Of course not. 20 billion yuan of R&D expenses need to be shared.
Assuming that this drug is expected to be replaced in 10, and 500,000 boxes are sold every year, a total of 5 million boxes will be sold. Therefore, it is necessary to allocate 5 billion yuan to 5 million boxes, and the unit R&D cost of each box is 4,000 yuan. So the actual cost of each box is 1000 yuan plus 4000 yuan equals 5000 yuan. In this way, selling for six or seven thousand yuan is not too much, is it?
In addition, many R&D will fail, and the related costs should also be included. For example, a drug invested 5 billion yuan in the early stage, and the research and development failed, and all 5 billion yuan was wasted. What do we do? We only share some drugs that have been successfully developed and mass-produced.
The price will drop a little after mass production, but it won't be too cheap. 1.2 million yuan of anticancer drugs are much more expensive than ordinary anticancer drugs, except for the high research and development costs in the early stage, but also because there is no mass production.
Why is cold medicine cheap? Because the more people use and the higher the sales volume, the more drugs can share the research and development costs. Still taking the above as an example, assuming that 50 million boxes of new drugs can be sold in ten years, then each box only needs to share the R&D expenses in 400 yuan; If we can sell 500 million boxes, we only need 40 yuan to share the cost.
Now the proportion of cancer patients is increasing, but compared with colds and fever, cancer patients are still a minority. Therefore, there is no way to share the R&D expenses by mass sales. Some rare drugs for treating diseases are more expensive, and even no pharmaceutical factory is willing to produce them because there are not many boxes to sell.
With more and more people using Aquiline injection, the production and sales of this medicine are increasing, and the price will also drop. But it can't be as cheap as cold medicine unless there are as many people who need it as there are people who need it.
Therefore, it is good that the price can be gradually reduced to less than 300,000 yuan, but 100 yuan is just impossible.
What about ordinary people? There are not many methods. Some people say social security. Social security is universal insurance, which plays the role of basic medical security and benefits hundreds of millions or even billions of people across the country. Social security can't solve high-end anticancer drugs for the simple reason that there is not so much money. This problem is very realistic, and so is foreign countries. Don't listen to foreign medical insurance, see a minor illness and make an appointment for a few months. In the end, you can either get better or spend more money on private hospitals. In addition, serious illness and expensive medicine also need personal responsibility.
The only solution is to buy commercial medical insurance. For the record, I don't sell insurance and I won't recommend insurance products. The purchase of commercial medical insurance is to prevent the huge expenditure of anticancer drugs. If you think commercial insurance is too expensive, you can buy various local Huimin insurance products. Although the coverage is not as large as that of ordinary commercial insurance, the basic anticancer drugs are guaranteed and the premium is very low.
In recent ten years, the word "cancer" has appeared more and more in front of people in China, dubbed as a terminal disease, and has become the first killer of people's health in China.
Anyone who has experienced the word cancer knows its power, that is, a battlefield that several generations have worked hard carelessly. In the face of cancer and huge medical expenses, how many families can face it calmly? Cancer is a knife hanging over the head of China's family. When the knife falls, it is a contest between money and fate.
The successful research and development of anticancer drugs is undoubtedly the expectation of cancer patients and the blessing of patients. The pain caused by cancer is incomprehensible to ordinary people, ranging from anxiety, irritability and depression to fear and even suicide.
But it seems to be to adjust the appetite of the general public or the people at the bottom of society, because it is a high-priced medicine that few patients can afford. No matter how advanced medicine is, if the ordinary mainstream people in society can't afford it, they won't get the universal effect of this advanced achievement. This advanced and costly practice is to instantly extinguish the hope that patients have just ignited. The cost of1.20 thousand/bag makes CAR-T cell therapy a "high-priced anticancer drug", and the voice of doubt is accompanied by abuse and pushed to the hot search.
From the enterprise's point of view, the high R&D expenses and technology patents forced them to make a price of1.20,000. If the price is too low, pharmaceutical companies can't survive, which is a blow to patients who can afford it. However, from the point of view of ordinary patients, the pricing of 1.2 million is very desperate.
In this society with a huge gap between the rich and the poor, the average also means that except for the rich at the top of the pyramid, ordinary people have to spend more money than their life savings, and even the savings of several generations are far from enough.
Personally, the medicine that the general public can afford is the lucky star of patients, otherwise it will increase the psychological pressure of patients.
If you really dare to pay such a high price, it is still of some use. If the bid is 100 yuan. I can't even afford to eat. Therefore, the high price policy of the United States has promoted the development of their new drugs. It is still in line with the laws of market economy.
1.2 million is really sky-high! But it's definitely not wild speculations! Any technology is constantly improving and perfecting!
First, let's think about it. What was the price of penicillin during World War II? The price of one gram of penicillin exceeds that of one gram of gold. At that time, there were only a few thousand units of penicillin, but now it is tens of millions of units. Why is the price so much cheaper! Because of the advanced culture and extraction technology of penicillin, the price is very cheap.
The second reason for the high price is the cost of research and development. The research and development of a new drug needs to invest tens of billions, and the cycle may be as long as several years or even more than ten years. These are all costs, which will be included in each dose. When the technology is more and more mature and the production efficiency is high, the cost of single dose sharing will also come down.
In China, one of our greatest abilities is to turn sky-high things into "cabbage prices". Let's wait and see! I believe that the researchers in our country will definitely make this new drug affordable for everyone.
As for the effect, any new drug is not so stable at the initial stage, and it needs to be verified by a series of experiments such as animal experiments and human experiments before it can be put into clinical use, and it is also adjusted and optimized at any time during use! Let the drug have better effects, less side effects and more affordable prices!
Let's not discuss how much a shot costs. What matters is the effect. How many injections can cure cancer? It seems that the poor can't count on 1.2 million. Whether the rich can see the official healing effect remains to be seen.