The treatment of heart failure includes both pharmacologic and nonpharmacologic therapies. Pharmacologic therapy can improve symptoms in some patients and reduce morbidity and mortality to some extent. However, heart failure is a chronic, progressive disease that requires long-term treatment. For patients who do not respond well to medication or who have more severe symptoms of heart failure, cardiac resynchronization therapy (CRT) can be used on the advice of a physician. CRT uses biventricular pacing to achieve optimal atrial AV delay and LV pacing to increase the diastolic filling time, synchronize the heart's left and right ventricular contractions, and resynchronize the contractions of the interventricular and intraventricular chambers to reduce mitral regurgitation and increase the per-passage output. A large amount of data show that CRT helps to improve the symptoms of heart failure patients, improve the quality of life, delay the course of the disease, improve the prognosis and reduce the mortality rate of patients, and is currently a more effective treatment for heart failure.