Ethylene oxide low-temperature sterilization system can be divided into gas mixture and 100 % pure ethylene oxide low-temperature sterilization system two kinds, the current use of all 100 % pure ethylene oxide low-temperature sterilization system. 1. Sterilization mechanism: ethylene oxide on bacteria (including Mycobacterium tuberculosis), bacillus, fungi, rickettsiae and viruses and other micro-organisms have a role in the killing, belongs to the broad-spectrum bactericidal agent. Its sterilization mechanism is with bacterial protein molecules, enzymes, nucleic acids in the amino, hydroxyl, carboxyl or sulfhydryl combination, the metabolism of the bacterial cell irreversible damage, so as to achieve sterilization effect.
2. Advantages: ① ethylene oxide is considered to be the best chemical sterilant, can kill all microorganisms including bacterial spores; ② strong penetration, can be used for a variety of difficult to penetrate the parts of the sterilization, such as some of the thinner, longer catheters, it is difficult to achieve sterilizing effect with other sterilization methods, can only be used with low-temperature sterilization or irradiation; ③ ethylene oxide microbial killing is the use of Alkylation principle, rather than oxidation process, so the damage to the goods is small, heat-resistant precision instruments sterilization has a very wide range of uses; ④ Sterilization of goods preserved for a long time, can be up to 336 d; ⑤ sterilization can be wrapped in a variety of packaging materials, easy to store, transport, open the package can be used; ⑥ there are perfect chemical and biological monitoring means, so that we can effectively control the quality of sterilization, and timely discovery of the failure of sterilization packages. The package.
3. Disadvantages: ① due to the need for longer ventilation time to remove the residual ethylene oxide, the entire sterilization cycle time is longer, generally need more than 10 h; ② ethylene oxide is toxic, is suspected of carcinogenicity, should be controlled in the indoor air concentration in the national standards, and the need for regular testing of the surrounding environment, the staff to carry out physical examination and tracking records;
③ ethylene oxide is toxic, is suspected of causing cancer, indoor air concentration control in the national standards, and need to regularly test the surrounding environment, staff check and track records;
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③Ethylene oxide is flammable and explosive, storage and sterilization must not leak, must choose a safe sterilizer, safe operation and storage; ④ due to the required purification process, special emission system, regular testing of the environment and regular staff checkups and tracking records, etc., its cost is relatively high. Hydrogen peroxide