Hunan Huarit Pharmaceutical Co., Ltd. was formerly known as Ningxiang County Pharmaceutical Factory in Hunan Province. It is located at No. 24, Baji Road, Yutan Town, Ningxiang County, Changsha City, Hunan Province.
Ningxiang Pharmaceutical Factory is a branch factory of Ningxiang Petrochemical General Factory, which was founded in 1979. In 1980, the production of pharmaceutical products, in 1987, the merger of the wood factory and the establishment of the Ningxiang Pharmaceutical and Chemical Plant, until 1992 to declare the Ningxiang Pharmaceutical Plant by the Provincial Department of Health, the provincial, municipal, pharmaceutical, pharmaceutical departments officially approved the Ningxiang Pharmaceutical Plant, and has the status of an independent legal person.
Production and management scope: antibiotic tablets, vitamin tablets, anti-inflammatory hormone tablets, disinfection and antiseptic ointment, dermatological preparations, anti-infective tablets, yellow, white Vaseline, brake fluid, medical potassium citrate, sodium citrate.
Pharmaceutical factory was established in the early years of the establishment of the initial development and production of sodium citrate, from the annual output of 1,000 tons, to gradually expand to 10,000 tons of production capacity, the highest year of production of 8,000 tons. Later on, it also developed the production of potassium citrate (pharmaceutical raw materials), the actual 1500 tons/year capacity, but the best years hovering around 1000 tons. Designed with an annual production capacity of 200 million tablets, the highest year in about 40 million tablets. There is also a production line for pharmaceutical yellow petroleum jelly with an annual capacity of 1,000 tons, as well as production facilities for ointment and dermatological drugs.
Since its establishment in 1987, the pharmaceutical factory has been committed to the development of citric acid series of products - citric acid, sodium citrate, potassium citrate (API), and has achieved better results, listed in the country at the time of the best level of the same industry, the quality of the product was awarded the provincial excellent products. The quality of the products was honored as provincial excellent products. 90% of the sales were exported, and the economic benefits increased year after year, which made the company a major backbone factory under the Petrochemical General Factory. In the production of pharmaceutical preparations, at that time has to meet the provincial market, mainly producing a small amount of oxytetracycline (tablets), erythromycin (tablets, ointment), urea soft (cream), benzalkonium bromide, prednisone acetate (tablets), xanthin hydrochloride (tablets) < berberine hydrochloride tablets>, vitamin B1 (tablets), vitamin C (tablets, injections), tetracycline (tablets, ointments, ointment), sulfur ointment, ichthyosine (ointment), iodine tincture and so on. (ointment), tincture of iodine, etc. Because of the market chaos at that time, often stop playing, drug production did not have great development, to 1995 basically all production. To Huaming brand citric acid (citric acid) series of products produced to date.
1996 is located in the downtown area of the pharmaceutical plant does not adapt to the needs of production development, and has an impact on nearby residents, students living and learning factors. The main plant decided to rebuild within the scope of the main plant. Plant covers an area of 10,000 square meters. In the second half of 1996 to complete the relocation. Due to the shortage of funds, in 1997 10 pharmaceutical plants in a state of shutdown.
May 25, 2001, Hunan Province, Drug Administration wholesale: on Agreeing to Ningxiang County Pharmaceutical Factory renamed the approval of the reply (Hunan Drug Administration Anfa [2001] No. 37). Agreed to Hunan Province, Ningxiang County Pharmaceutical Factory renamed Hunan Huarizhi Pharmaceutical Co. And on July 3, the same year wholesale Xiang Drug Administration Note [2001] No. 213: Hunan Province, Ningxiang County Pharmaceutical Factory of drug approval number attributed to Hunan Huarit Pharmaceutical Co.
Hunan Huarit Pharmaceutical Co., Ltd. is a subsidiary of Hunan Yinhai Petrochemical Co. It is located at No.16 Jinting Road, Ningxiang County, Hunan Province, and the factory is within the scope of Hunan Yinhai Petrochemical Group, covering an area of 26,000 square meters. The power supply is supplied by 35KV substation of Yinhai Group, in which there are 2 sets of 20-ton boilers and 2 sets of 10-ton boilers for steam, a pumping station at Weishui River with an upward water volume of 1,200 cubic meters/hour, and 2 sets of air compressors (6 cubic meters/minute). The area has convenient transportation, perfect production conditions and elegant environment. The company produces citrate series of API and solid preparation products. Its production scale: 400 tons/year of citric acid, 100 tons/year of sodium citrate, 100 tons/year of potassium citrate. Citrate series of APIs have a long history, citrate registered in 78 years, sodium citrate registered in 89 years, and won the national patent, potassium citrate registered in 94 years, won the provincial excellent new products. 2002, all upgraded to the national drug approval number. Its company in the total number of 168 employees, engaged in the production of 140 people, 28 managers, 43 production technicians, including 4 people with bachelor's degree, 11 people with college education, 14 people with secondary school education, 2 engineers engaged in the production of a long time, a registered licensed pharmacist, engaged in the quality of the inspection of 15 people.
In 2002, the company invested 30 million dollars to carry out the GMP workshop renovation of solid preparations. The production capacity reaches 100,000,000 capsules, 60,000,000 packages of granules, and the output of tablets reaches 300,000,000 tablets.
July 16, 2004 - July 18, 2004 Hunan Food and Drug Administration for GMP on-site certification. August 13, 2004 passed the API (citrate, sodium citrate, potassium citrate) GMP certification (Xiang F0055), is the first in the country through the GMP certification of citrate series.
Hunan Huarizhi Pharmaceutical Co., Ltd. now covers an area of 12,000 square meters, with a building area of 4,880 square meters, a production building area of 373 square meters, a warehousing area of 650 square meters, a quality inspection room area of 300 square meters, an administrative office area of 150 square meters, and an auxiliary room area of 50 square meters. Subordinate boutique workshop (5000 tons/year), sodium citrate workshop (500 tons/year), potassium citrate workshop (150 tons/month), tablet workshop, Vaseline workshop. There are fifteen existing approvals, 11 normal production, fixed assets of 850,000 yuan. It mainly produces APIs Citrate, Sodium Citrate, Potassium Citrate, Calcium Citrate and Antibiotics, Vitamins, Anti-inflammatory Hormones, Tablets, Capsules, Granules, Disinfecting and Antiseptic Ointment, Dermatological Preparations, Yellow and White Vaseline, and so on. The company has 50 personnel, including 1 graduate student, 2 licensed pharmacists, 10 people with bachelor's degree, 19 people with college and secondary school education.
In August 2007, the company began the overall relocation to the new site (Ningxiang County Economic Development Zone, the Second Ring East Road), the overall relocation, the organization is perfect, the rules and regulations are complete, the operating procedures are clear, the product production process control is tight, in line with the requirements of GMP certification of pharmaceuticals, from December 25, 2007 to December 26, 2007, Hunan Food and Drug Administration for GMP On-site certification. And on December 25, 2007 again through the API (anhydrous citric acid & lt; State Drug Administration H20070012 & gt;, citric acid & lt; State Drug Administration H43020597 & gt;, potassium citrate & lt; State Drug Administration H43020598 & gt;, sodium citrate & lt; State Drug Administration H43020599 & gt;) GMP certification (Xiang J0222).
Hunan Huarizhi Pharmaceutical Co., Ltd. is a subsidiary of Hunan Changsha Shenghai Group with independent legal personality, the company is located in the second ring east road of Changsha City, Ningxiang County, Jingkai District, the factory is in the Shenghai Group, the company's registered capital of 5 million yuan, occupies an area of 100,000 square meters, the workshop floor area of 3,700 square meters, the laboratory area of 500 square meters, the area of 240 square meters of clean room. The area has convenient transportation and perfect production supporting conditions.
The company has 70 personnel, including 20 technicians, 7 managers, 8 inspection analysts, 3 quality control personnel. Production and quality management personnel are highly specialized. Main production equipment: dissolving tank, coarse filter, fine filter, concentration and crystallization tank, centrifuge, dryer, vibration sieve, purified water system. Main analytical instruments: infrared spectrophotometer, ultraviolet spectrophotometer, moisture meter, muffle furnace, oven, ultra-clean bench, analytical balance,, electronic balance, PH meter, photometer, conductivity meter, acid meter, spin meter, etc..
On April 19, 2007, we obtained the new drug certificate of anhydrous citric acid (State Drug Permit H20070012)
On March 10, 2009, we obtained the registration approvals of Sorbic Acid (Xiangshang Food and Drug Auxiliary Permit F20090015) and Sodium Benzoate (Xiangshang Food and Drug Auxiliary Permit F20090014).
On September 16, 2009, the registration approval of Sodium Cyclamate (F20090046) was obtained.
On Sep. 17, 2009, Stearic Acid (Xiangfeng Pharmaceutical Auxiliary Quarantine F20090045) and Magnesium Stearate (Xiangfeng Pharmaceutical Auxiliary Quarantine F20090044) were approved for registration.
On October 28, 2009, we obtained the registration approval of Sodium Acetate (Xiangfood Drug Auxiliary Quarantine F20090049).
On Nov. 4, 2009, the registration approval of Sodium Sulfite Anhydrous (F20090050), Disodium Edetate (F20090051) and Potassium Sorbate (F20090052) was obtained.
On November 6, 2009, the Board of Directors of Shenghai Group decided to assign another refining production workshop under the Group for the production of citric acid series products to Hunan Huarizhi Pharmaceutical Co., Ltd. as the second production line for the production of APIs, and the same production of six varieties of APIs such as Citric Acid, Sodium Citrate, Potassium Citrate, Citrate anhydrous, Boric Acid, Borax and so on.
On November 25, 2009, we obtained the registration approvals for the APIs boric acid (State Pharmaceutical Approval Number H20094111) and borax (State Pharmaceutical Approval Number H20094124).
On February 25, 2010, we passed the GMP certification of API (anhydrous citric acid, citric acid, potassium citrate, sodium citrate, boric acid, borax) again (Xiang L0345).
Hunan Huarih Pharmaceutical Co., Ltd. under the API production of a workshop (the production of boric acid, borax, citric acid, citric acid, citric acid, sodium citrate, potassium citrate, anhydrous citric acid, sorbic acid, sodium benzoate), API production of two workshops (the production of boric acid, borax, citric acid, citric acid, sodium citrate, citric acid, potassium citrate, anhydrous citrate), the production of medicinal excipients in a workshop (the production of potassium sorbate, sodium acetate, edetate disodium, anhydrous sodium sulfite, cyclic sulfuric acid, cyclic acid disodium). Anhydrous Sodium Sulfite, Sodium Cyclamate, Stearic Acid, Magnesium Stearate), the company built a new workshop of 3,700 square meters at the end of 2009. It is expected that the new products will be put into operation at the end of 2011. The second workshop of API production is about 200 meters away from the first workshop of Huari-Pharmaceutical, and the surrounding environment has been well greened, no exposed land surface, all within the group company's factory, which is a refining workshop specializing in the production of citric acid series products in accordance with the requirements of Japan's East Cotton Company Limited. Its production equipment is in line with the requirements of the production process of the existing API varieties (boric acid, borax, citric acid, sodium citrate, potassium citrate, anhydrous citric acid) of Huari-Pharmaceutical. The workshop covers an area of 324 square meters,**** divided into six floors. The total area of the 300,000-grade clean area of the second workshop for raw material production is 100 square meters, with an independent air purification system. This clean area is mainly used for product packaging and internal packaging. Other processes are carried out in the closed equipment system from fine filtration. There are 16 sets of major large equipment*** in this workshop, and all the feeding pipes and equipment are made of stainless steel (316L), which is in line with the GMP production requirements.
Now Hunan Huarizhi Pharmaceutical Co., Ltd. has a production capacity of 3,500 tons/year for API workshop; 400 tons/year for pharmaceutical excipients. The company is dedicated to providing customers with high-quality products and good after-sales service.