Secondly, the sterilization of aseptic rooms requires the use of at least two different disinfection methods alternately, which are commonly used surface wipe disinfectants such as 75% ethanol, Gelsemium, ethylene oxide, etc.; and chemical fumigation of the air and surfaces in the workshop at the same time disinfection, ozone can be used, formaldehyde, gaseous hydrogen peroxide and other strong oxidizing gases disinfection. Aseptic workshop does not consider the use of ultraviolet lamps or radiation sterilization, the former disinfection is too poor, the latter for safety reasons are generally not used for environmental disinfection.
And food sterilization equipment, most of the use of ozone, ultraviolet light or radiation sterilization, the surrounding environment does not require sterility, disinfection requirements are not as stringent as the sterility requirements.
The determination of the disinfection effect, generally using biological indicators, that is, with a known number of bacteria contained in the standard bacterial slice or bacteria, the use of your specified disinfection method or equipment for disinfection, and then after the disinfection of the standard bacterial samples taken to the culture, if the culture of bacteria, that is, the disinfection of incomplete, if after the culture of bacteria-free generation, that is, the disinfection is complete. The higher the concentration of bacteria in the initial sample, the greater the challenge to the bactericidal efficacy of the disinfection method, i.e. the more stringent its requirements. Biological indicators used in the food industry generally use 10 of the third to the sixth power of the bacterial concentration, and the effectiveness of chemical fumigation of the GMP aseptic workshop is required to be able to kill 10 of the sixth power concentration of the standard bacteria samples.