The Fourth Affiliated Hospital of Harbin Medical University, formerly known as the Dongqing Railway Central Hospital, was founded in 1903 and changed its name several times, changing its name to Harbin Railway Central Hospital in 1953, and then merging into Harbin Medical University and changing its name to the Fourth Affiliated Hospital of Harbin Medical University in 2004.
The Fourth Affiliated Hospital of Harbin Medical University has been designated as the "rehabilitation guidance station of Harbin Cancer Rehabilitation Association" since 2013, and is the training base of the Ministry of Health for specialists and the training base of the Ministry of Health for clinical pharmacists. In 2013, the hospital was designated as the "Harbin Cancer Rehabilitation Association Rehabilitation Guidance Station", the hospital is the Ministry of Health Specialist Training Base, the Ministry of Health Clinical Pharmacist Training Base, Heilongjiang Province, professional and technical personnel training base for continuing education, the first batch of national Grade 3A hospitals, the country's top 100 hospitals.
With the vigorous development of biotechnology in the medical field, the hospital has followed the cutting-edge science and technology, invested heavily in the purchase of a large number of advanced medical laboratory equipment, and introduced CLS tumor biotherapy technology, which is a representative technology in the field of tumor biotherapy, and set up the Center for Tumor Bio-Therapy of the Fourth Hospital of Harbin Medical University.
The center has a strong medical team, from cell culturists to authoritative bio-immunity experts, the proportion of doctoral and master's degree and other highly educated talents is up to more than 50%, including five doctoral supervisors and three master's supervisors. The center will be docked with the national biological treatment consultation platform through advanced telemedicine system, and the authoritative biological anti-cancer experts in the United Nations will carefully design the treatment plan for the tumor patients on a one-to-one basis. In the spirit of "people-oriented, the pursuit of excellence", relying on cutting-edge biotechnology, the center will serve patients with CLS biological anti-cancer technology as the leading technology and CLS psychological intervention therapy as the auxiliary technology, and will take care of patients' physical and mental health in an all-round way.
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Concept of Tumor Biotherapy
Biotherapy refers to the therapeutic method of inhibiting or preventing tumor growth, metastasis, and recurrence by mobilizing the body's defense mechanism or with the help of biologics to regulate the body's immune system and enhance the ability of anticancer, thus achieving the goal of inhibiting or preventing tumor growth, metastasis, and recurrence. Biotherapy is also the fourth major tumor modality after surgery, radiotherapy and chemotherapy, and because of its safe, effective and non-toxic side effects, it is considered to be the most active and promising therapeutic means in the comprehensive treatment of tumors in the 21st century.
CLS tumor biotherapy technology
CLS biological anti-cancer technology is the earliest biotherapy technology applied to the field of tumor clinical treatment on a large scale in China, which utilizes DC immunotherapy and CIK immunotherapy as well as DC-CIK immunotherapy to eliminate cancer cells.
DC is the dendritic cell, which is the most effective and functional antigen-producing cell in the body, transmits anti-cancer information, effectively activates and mobilizes anti-cancer cells in the body to kill tumor cells.
CIK cells are cytokine-induced killer cells, which directly kill tumor cells by exerting their own cytotoxicity and secreting cytokines. In clinical application, the two are often combined to cultivate biclonal immune cells, which have more powerful anti-tumor properties. DC-CIK immunotherapy.
The process of CLS tumor biotherapy
Peripheral blood mononuclear cell collection → in vitro cell isolation → in vitro induction, activation, culture and expansion of DC cells and CIK cells → quality control → biological activity measurement → DC-CIK cell preparation and transfusion of treatment → follow-up. Each course of treatment (cell collection to the end of infusion)*** takes about 15 days.
Features of biological therapy
1, the most inclusive: biological therapy has a strong inclusiveness, applicable to all malignant tumors except T-cell lymphoma.
2. The most safety: since the patients' own immune cells are used to fight against cancer, there is no rejection and side effects, which is greatly different from the previous pattern of "killing a thousand cancers and damaging eight hundred" in the treatment of tumors, and it is safe and non-toxic, which is the real meaning of "green anticancer". It is safe and non-toxic, which is the real meaning of "green anti-cancer".
3. The most guaranteed: no matter it is early, middle or late stage tumor, biological therapy can get ideal therapeutic effect. According to some data, the clinical cure rate of patients receiving biological treatment reaches 72%, while the clinical cure rate of patients not receiving biological treatment is only 40%. Those patients who are inoperable, intolerant and insensitive to radiotherapy are more suitable for biological treatment.
Advantages of CLS tumor biotherapy
When tumor biotherapy is combined with surgery and radiotherapy, the following effects can be achieved:
1. It can effectively remove residual tumor cells and tiny foci after surgery and radiotherapy, and prevent recurrence and metastasis of tumor.
2. It can enhance the sensitivity of radiotherapy and reduce the toxic side effects of radiotherapy; resist the immunosuppressive effect of chemotherapeutic drugs, enhance the sensitivity to chemotherapeutic drugs and improve the efficacy of chemotherapy.
3. Due to the immune regulation and body cell repairing effect of biological therapy, most patients, especially those after radiotherapy, can experience "rejuvenation" such as reduction or disappearance of gastrointestinal symptoms, glossy skin, fading of dark spots, disappearance of varicose veins, stopping of alopecia and hair loss, and change of white hair into black hair while treating tumors, and mental state and physical strength. The mental state and physical strength also have obvious recovery, which greatly improves the quality of life of tumor patients.
4. For patients with advanced tumors who have lost the chance of surgery or whose tumor cells have relapsed or metastasized, CLS can rapidly alleviate their clinical symptoms, and most of the patients will experience shrinkage or even disappearance of their tumors or long-term survival with tumors; for patients who have no effect of radiotherapy or who are resistant to chemotherapeutic drugs, CLS can be applied to prolong their survival period. Indications of CLS tumor biological therapy
Biological therapy is applicable to a variety of solid tumors, including malignant melanoma, prostate cancer, renal cancer, bladder cancer, ovarian cancer, rectal cancer, breast cancer, cervical cancer, lung cancer, laryngeal cancer, nasopharyngeal carcinoma, pancreatic cancer, hepatocellular carcinoma, gastric cancer, and other solid tumors to prevent recurrence after surgery, and it can be used for the recurrence of hematological malignant tumors, such as multiple myeloma, lymphoma, leukemia, etc., and it can be used for the further consolidation of the above mentioned tumors. It can also be used for further consolidation treatment of the above tumors to achieve the purpose of prolonging survival, improving life treatment and controlling tumor deterioration.