1, the mechanism of action is different:
Recombinant human interferon a-2a bolus: mainly through the interferon and target cell surface interferon receptor binding, inducing the target cells to produce 2-5 (A) synthetase, protein kinase PKR, MX protein and other antiviral proteins, to prevent the synthesis of viral proteins.
Recombinant human interferon a-2b bolus: It has broad-spectrum antiviral, inhibits cell proliferation and other effects, and improves immune function.
2, side effects are different:
Recombinant human interferon a-2a bolus: toxic side effects are very small.
Recombinant human interferon a-2b suppositories: slight lower abdominal swelling and lumbago may occur after use.
Extended information:
Mechanism of action of recombinant human interferon a-2a suppository and recombinant human interferon a-2b suppository:
Pharmacology: recombinant human interferon a 2a has a broad-spectrum antiviral effect, and its antiviral mechanism is mainly realized through the binding of interferon to the interferon receptor on the surface of target cells, inducing the production of 2-5(A) synthase, protein kinase PKR, MX protein and other antiviral proteins in the target cells, preventing the synthesis of viral proteins, and inhibiting viral nucleic acid replication and transcription. Interferon also has multiple immunomodulatory effects, which can improve the phagocytic activity of macrophages and enhance the specific cytotoxicity of lymphocytes to target cells, etc., to promote and maintain the body's immunosurveillance, immunoprotection and immune self-stabilization functions.
Recombinant human interferon α2b has broad-spectrum antiviral and cell proliferation inhibition effects, and can improve immune functions, such as enhancing phagocytosis of macrophages, improving cytotoxicity of lymphocytes to target cells and enhancing the function of natural killer cells.
Baidu Encyclopedia - Recombinant Human Interferon α2b Suppository
Baidu Encyclopedia - Recombinant Human Interferon α-2a Suppository