What are the cleaning agents and disinfectants in GMP regulations for drug manufacturing?

Sanitizers: 2% or 3%-5% Lysol, 75% ethanol, 0.1-0.2% Neosporin, Dow 0.05-version 0.1% Dumefen, 0.02%-0.05% Chlorhexidine, 0.2% -0.5% peroxyacetic acid, 37%-40% formaldehyde.

Detergents: detergent, 1% sodium hydroxide, hand sanitizer and so on.

Aldehyde disinfectants include formaldehyde and glutaraldehyde. This type of disinfection principle for a lively alkylating agent acts on the amino, carboxyl, hydroxyl and sulfhydryl groups in microbial proteins, thus destroying the protein molecules and causing microbial death.

Formaldehyde and glutaraldehyde can kill a variety of microorganisms, because they have stimulation and curing effect on human skin, mucous membranes, and can sensitize people, so it can not be used for air, eating utensils and other disinfection, generally only used in hospitals to disinfect or sterilize medical equipment, and the disinfected or sterilized items must be sterilized with sterilized water will be rinsed out of residual disinfectant solution can be used only after.

Expanded Information:

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There are no hard and fast rules for cleaners and sanitizers. Cleaning agents such as water and SDS should be single component substances. You can't use mixtures like detergents. Disinfectants are commonly used: 75% alcohol, Neosporin, Chlorhexidine, etc.

Commonly used disinfectant products in order to classify the composition of the main nine: chlorine disinfectants, peroxide disinfectants, aldehyde disinfectants, alcohol disinfectants, iodine-containing disinfectants, phenolic disinfectants, ethylene oxide, bisguanidine disinfectants and quaternary ammonium disinfectants.

The main ingredient of detergents is surfactants, which are mainly used to wash oil and other dirt. There are a variety of disinfectants, generally a variety of bactericides, such as 84 disinfectant is known to be the road oxidant, Lysol disinfectant is a mixture of carbolic acid and soap, alcohol disinfectant is 75% alcohol soluble in liquid. In general, these disinfectants have no, or very little, washing effect.

Baidu Encyclopedia - Detergents

Baidu Encyclopedia - Sanitizers