Rest, eat a soft, digestible and nutritious diet and supplement multivitamins. Blood transfusion can be given to those with severe anemia, and fluid replacement should be given to those with severe diarrhea to correct electrolyte disorder.
Drug therapy:
Sulfasalazine 1.0g, 4 times /d, smecta 3.0g, 3 times /d, butanol 165mg, 3 times /d, hydrocortisone 50- 100mg can be used for low-level patients, and 60 enema is reserved. Moderate and severe patients can take oral prednisone 40mg/d or intravenous drip of hydrocortisone sodium succinate 300mg/d, and the symptoms will gradually decrease after improvement. Sometimes broad-spectrum antibiotics are needed to control secondary infections.
Surgical treatment:
Intestinal perforation, severe bleeding, intestinal obstruction, canceration, multiple polyps, toxic Hirschsprung's disease, pericolonic abscess or fistula formation can be treated surgically.
Orexin-Balsalazide Sodium Capsule in the Treatment of Colitis
Ulcerative colitis, also known as nonspecific ulcerative colitis, is a colorectal disease. The clinical manifestations are unexplained diarrhea many times a day, accompanied by bloody stool or mucus stool and abdominal pain, most of which are recurrent and induced by diet and spirit.
Diagnosis: A complete diagnosis includes its clinical course, disease degree, lesion range and disease stage. Persistent or recurrent abdominal pain, diarrhea and bloody stool are accompanied by different degrees of systemic symptoms. Infectious enteritis and Crohn's disease such as dysentery, amebic dysentery and intestinal tuberculosis were excluded, and the diagnosis of this disease was made by barium enema colonoscopy.
Treatment: sulfasalazine, glucocorticoid, immunosuppressant. Balsalazide is a special preparation of 5-ASA developed in recent years, which is composed of 5-ASA and azo bond. It decomposes and releases a large number of effective components in colon, thus improving the curative effect and reducing the side effects, with the disadvantage of high price. Balsalazide sodium was developed by Biorex company in the early days, and Astriu Pharmaceutical Co., Ltd. was listed in the UK for the first time. Orexin-Balsalazide sodium provides more choices for patients with colitis, colonic ulcer and localized enteritis.
Diet therapy for ulcerative colitis
Dietary principles and requirements
Ulcerative colitis is a chronic colitis disease with unknown causes. Lesions are mainly confined to colonic mucosa, mainly ulcers. Its main symptoms are abdominal pain and diarrhea, and stool is often accompanied by blood pus and mucus. Stool 2-4 times a day, more than 10 times in severe cases. Patients often show malnutrition, emaciation and anemia. Because ulcerative colitis is a chronic disease that needs long-term treatment, it is very important to adjust nutrition and diet. The general principle is a diet with high energy, high protein, high vitamins, less oil and less residue.
1. High energy and high protein can make up for the nutrient consumption caused by long-term diarrhea, and gradually increase the supply according to the digestion, absorption and tolerance of patients. Generally speaking, it provides 40 kilocalories of heat per kilogram of body weight every day. Protein's daily weight per kilogram 1.5g, of which 50% should be high-quality protein.
2. Vitamin inorganic salts should be enough to make up for the nutritional loss caused by diarrhea.
3. Limit fat and dietary fiber: Diarrhea is often accompanied by fat malabsorption, and severe cases are accompanied by fatty diarrhea. Therefore, we should limit the amount of dietary fat and eat less greasy food and cooking methods. For patients with fatty diarrhea, medium-chain fatty acid grease can be used. Avoid eating foods containing irritation and high fiber, such as spicy food, sweet potatoes, radishes, celery, raw vegetables and fruits, and irritating onions, ginger, garlic, coarse grains, dried beans, etc.
4. Eat less and eat more: In order to reduce the burden on the intestines, we should supplement the nutritional intake by eating less and eating more.
5. Diet: 1. Use liquid food or semi-liquid food with little residue before and after acute attack or after operation. Food content: rice soup, steamed eggs, flour and milk are generally not recommended. Vegetables and fruits must be banned. Can be made into vegetable water, vegetable puree, fruit juice, fruit puree, jelly, etc. Less residue and half flow can be made of high-quality protein fish, lean meat and eggs into soft and less oily foods, such as fish balls, lotus seed porridge, shredded chicken Longxu Noodles, bread, etc. 2. For those who are seriously ill and can't take it orally, tube feeding or intravenous nutrition support can be used, and natural food will be taken orally gradually after the nutritional status improves.
1, supply enough protein, inorganic salts and vitamins, avoid malnutrition and hypoproteinemia as much as possible to enhance physical fitness, which is beneficial to the relief of diseases.
2. Avoid irritating and fiber-rich foods, such as spicy foods such as peppers and mustard, and foods rich in residues such as sweet potatoes, radishes and celery. Avoid eating raw vegetables, fruits and irritating condiments such as onions, ginger and garlic. Knife should be thin, don't cook with large pieces of meat, always use minced meat, diced meat, shredded pork, minced meat, steamed egg soup, boiled eggs and so on. And try to limit the dietary fiber such as leek, radish and celery.
3. It is recommended to take "Yongcang Hu Ling antidiarrheal capsule" for diarrhea. Do not eat greasy food and fried food. Cooking all kinds of dishes should use steaming, boiling, stewing and water skiing as little as possible. Black tea, burnt rice porridge soup and other astringent drinks can be used. Eat a small amount of rice to increase nutrition.
In the process of diet conditioning, patients and their families should pay attention to their illness and the influence of food on patients. If patients feel uncomfortable or have allergic reactions after eating any food, they should sum up their experience in time and constantly explore a diet suitable for patients. It is not advisable to eat vegetables and fruits at the time of onset, and pay attention to properly supplementing vitamins to ensure the body's demand for vitamins.
cookbook
1: Breakfast: 250g milk and yogurt, 50g steamed bread.
Lunch: noodles 125g minced cucumber (minced meat 100g peeled cucumber 100g tofu) and shrimp skin (50g shrimp skin 10g tofu).
Meal: 50g of soda crackers with lotus root starch (25g of lotus root starch).
Dinner: millet porridge (50g of millet), flower rolls (50g of flour) and shredded Chinese cabbage (50g of shredded pork 100g of lean meat).
All-day edible oil 25g
2. Breakfast: Millet porridge boiled with tender eggs and minced meat.
Diet: skim yogurt, biscuits
Lunch: Steamed fish with rotten noodles and braised tofu.
Extra meal: steamed eggs
Dinner: rice porridge, rolls, shredded pork, shredded chicken, steamed eggs.
Extra meal: make thin lotus root starch cookies
3. Breakfast: Millet porridge boiled with tender eggs and minced meat.
Extra meal: steamed egg cake
Lunch: Longxu Noodles chicken balls and braised tofu.
Dinner: Braised fish slices, eggs and white rice porridge steamed bread.
Extra meal: make thin lotus root starch cookies
1.Aurexin-Balsalazide sodium capsule successfully applied the polymer film coating technology originally created by Astra Salix in Britain to form 5-ASA microparticle preparation.
2. Orexin-Balsalazide sodium capsules release drugs in the inflammatory site in a targeted way, which can exert the curative effect of 100% without loss and reduce adverse reactions to the body.
3. Orexin-Balsalazide sodium capsules are insoluble in gastric acid, maintain effective activity and enter the colon.
4. Orexin-Balsalazide sodium capsule is the only drug that can effectively inhibit the pathogenic factors of colitis and ulcer (the metabolite of arachidonic acid), which has a strong anti-inflammatory effect and eliminates the root cause of inflammation.
5. Orexin-Balsalazide sodium capsule is the only drug that can scavenge oxygen free radicals, improve intestinal function, repair the surface of inflammatory ulcer, and combine sterilization to achieve dual effects of anti-inflammation and repair.
In the treatment of colitis and ulcerative colitis, it can be said that only a few soldiers can take advantage of it, and only a few drugs can take effect.
Edit this paragraph | Return to the top of the diet principle Selective colitis is a chronic colitis with unknown causes, mainly confined to the colonic mucosa, characterized by inflammation or ulcer, which mostly involves the rectum and distal colon but can spread to the proximal end or even the whole colon.
The etiology of ulcerative colitis is not completely clear. At present, it is believed that the pathogenesis of ulcerative colitis is mainly due to the abnormal immune mechanism, cellular and humoral immune response, and is related to genetic factors. Infection and mental factors may be related to the onset. The main clinical manifestations are diarrhea, bloody stool, abdominal pain and acute diarrhea.
The onset of ulcerative colitis is slow, and it is usually a chronic protracted process. The course of the disease is long and the symptoms appear repeatedly, which can be delayed for several years to more than ten years. Mental stimulation, fatigue and eating disorders are the main causes of this disease.
Because the cause of this disease is still unclear, long-term recurrent attacks often make people feel a heavy psychological burden. A correct understanding of the disease and self-care from rest, diet and rational medication are conducive to preventing recurrence, controlling the development of the disease, and relieving it until it is cured. Those who are light can work and live a regular life, pay attention to the combination of work and rest, keep a happy mood and prevent intestinal infection. Dietary intake of high calorie, high nutrition, less fiber, less stimulation, low fat and digestible food; Avoid eating food suspected of intolerance, such as shrimp, soft-shelled turtle, peanuts, etc. Milk will aggravate diarrhea, so milk and dairy products should be avoided; Avoid eating peppers, freezing cold food, and quitting smoking and drinking. It is necessary to know the importance of insisting on taking medicine, the specific methods of taking medicine and related side effects in order to use medicine correctly. If you have diarrhea, abdominal pain, bloody stool and other abnormal conditions, you should go to the hospital in time to avoid delaying treatment.
The latest drug treatment is effective.
"Yongcang Heling Zhixie Capsule" is a famous prescription in Treatise on Febrile Diseases by Zhang Zhongjing, a medical sage, and is refined by the most advanced nano-extraction technology in the world. This prescription is composed of fourteen kinds of Chinese medicines, such as musk, poppy shell, etc. , in strict accordance with the traditional Chinese medicine prescription' monarch, minister, assistant and envoy' scientific compatibility. The first effective drug for treating colitis in China. The successful appearance of this medicine has broken enteritis and colitis, and ulcerative colitis can only control the incurable problem. For about 45 days, it can eliminate virus, promote blood circulation to reduce swelling, promote qi circulation to relieve depression, soothe the liver and strengthen the spleen, improve gastrointestinal dysfunction, promote intestinal mucosa regeneration and repair, and improve immunity. In about 60 days, the harmful flora causing the disease will be eliminated, and the colon defense function will be increased, thus achieving the goal of radical treatment of colon diseases.
Edit this paragraph | Hui Ding TCM treatment of ulcerative colitis is a pathological change with unknown etiology, mainly non-specific inflammation and ulcer formation of rectum and colon mucosa. The main clinical symptoms are abdominal pain, diarrhea, acute diarrhea and mucus purulent bloody stool.
What is ulcerative colitis?
Ulcerative colitis was first reported in 1875. 65438-0973 The International Organization Committee of the World Health Organization named this disease as idiopathic colitis, also known as chronic nonspecific ulcerative colitis, to distinguish it from various specific inflammations. However, due to clinical consistency, scholars at home and abroad still use the name of ulcerative colitis.
This disease is statistically significant. Because of the long course of disease and different severity, it is often easy to relapse. According to statistics, the incidence of this disease is relatively high in Europe and America, accounting for 40/65438+ 10,000 ~ 100/65438+ 10,000; The incidence rate is about 3/ 1 ten thousand ~ 1 1.5/ 1 ten thousand. At present, there is no accurate statistical report data in China, but it seems to be increasing in recent years. Clinically, it is more common in people aged 20 ~ 40, and there is no significant difference in incidence between men and women.
Diagnostic basis of ulcerative colitis
Enteritis is based on the Diagnostic Classification and Treatment Criteria of Chronic Nonspecific Ulcerative Colitis formulated by Anorectal Society of the All-China Society of Traditional Chinese Medicine. 1987.
(1) Clinical features: chronic mucus stool, bloody stool, abdominal pain, chronic recurrence or persistence, accompanied by different degrees of systemic symptoms. A few patients with enteritis just have no bloody stool. Pay attention to the clinical manifestations of joints, mouth, eyes, serosa, skin, liver and spleen in the physical examination of past history.
(2) Colonoscopy of sigmoid colon or fibrocolonoscopy showed that: ① the colonic mucosa showed multiple superficial ulcers, accompanied by congestion and edema; Lesions usually begin in the rectum and often involve the colon, showing diffuse distribution. ② The appearance of intestinal mucosa is rough and uneven, showing fine particles, and the tissue is fragile and easy to bleed, or it can be covered with thick secretions, which seems to be accompanied by a thin layer of moss. ③ The colonic sac is often flattened or blunted, so that the button-shaped sac disappears, and sometimes multiple pseudopolyps of different sizes can be seen. ④ Pathological changes of colonic mucosa biopsy showed inflammatory reaction, and mucosal erosion, crypt abscess, abnormal arrangement of colon glands and epithelial changes were often seen.
(3) Barium enema can be seen as follows: ① The colon tube is shortened, the colon bag disappears, or the colon is tubular. ② Recurrent ulcer or multiple pseudopolyps. ③ The colonic mucosa is rough, disordered or granular.
(4) Pathological examination: Specific infectious colitis, granulomatous colitis and radiation colitis such as bacillary dysentery, amoebic dysentery and schistosomiasis were excluded.
(5) Judgment method: ① The disease can be diagnosed according to the clinical aspects and one of sigmoidoscopy or fibrocolonoscopy and/or mucosal biopsy (1), (2) and (3). ② One of the three items (1), (2) and (3) can be diagnosed by combining clinical aspects and barium enema. ③ The diagnosis is established if the clinical manifestations are atypical, but there are typical changes in colonoscopy or barium enema. ④ Patients with typical clinical symptoms or typical past history, but with no typical changes in this sigmoidoscopy, fibercolonoscopy or barium enema examination, should be classified as "suspected diagnosis" and should be followed up.
Etiology of ulcerative colitis
This disease is a digestive tract disease with unknown etiology, mainly superficial and nonspecific inflammatory lesions of rectum and colon, mainly involving rectum and sigmoid colon, and also invading other parts or all of colon. Among patients with severe lesions, a few patients may have "reflux ileitis" in the range of 10cm, most of them invade mucosa and submucosa, and rarely involve muscularis. First, diffuse inflammatory changes of superficial mucosa, extensive congestion, followed by edema aggravation, hypertrophy and brittleness. Most abscesses can form superficial small ulcers and then develop into large ulcers, which is the characteristic of this disease. In the later stage, due to the proliferation of colon tissue, the intestinal wall became thicker and narrower, and the intestinal tube became shorter.
What are the types and characteristics of ulcerative colitis?
Ulcerative colitis can be classified into two categories, namely, according to the severity of ulcerative colitis and according to the course of ulcerative colitis.
According to the severity of ulcerative colitis, it can be divided into three grades:
(1) Mild: This type is the most common and usually only involves the distal colon. The illness is mild, with diarrhea less than 4 times a day, abdominal pain and bloody stool, and lack of systemic symptoms and signs.
(2) Moderate: between mild and severe, with sudden onset. Diarrhea 4-5 times a day, with loose stool and bloody stool, severe abdominal pain, low fever, weight loss, loss of appetite and parenteral manifestations.
(3) Severe illness: sudden onset, obvious diarrhea, bloody stool, persistent severe abdominal pain, hypotension and even shock.
According to the course of ulcerative colitis, it can be divided into the following four types:
(1) Initial onset: refers to the first attack, with no previous medical history, and the severity of illness varies, which can be converted to other types.
(2) Chronic recurrence type: it is the most common type in clinic, with small lesion range, mild symptoms and often remission period, but it is easy to relapse and has a good prognosis. Most of them are effective against salicylic acid and sulfasalazine.
(3) Chronic persistence: wide range of lesions. After the first attack, there may be mild diarrhea and bloody stool, which often lasts for more than half a year, and there may also be acute attacks.
(4) Acute explosive type: rare, sudden onset, severe local and systemic symptoms, often accompanied by high fever, watery diarrhea, acute colon dilatation, and prone to complications such as lower gastrointestinal bleeding and intestinal perforation. Fulminant cases need corticosteroids and blood transfusion treatment, and the prognosis is poor. Some patients with ulcerative colitis will often die within 2 weeks if they are not treated in time.
Clinical manifestations of ulcerative colitis
The main clinical symptoms are sticky mucus, purulent bloody stool, abdominal pain, diarrhea or acute diarrhea. Patients with acute critical cases have systemic symptoms, often accompanied by parenteral diseases and liver damage, arthritis, skin damage, myocardial lesions, multiple oral ulcers, iridocyclitis and endocrine diseases.
Traditional Chinese Medicine Treatment of Ulcerative Colitis
Ulcerative colitis is a disease of unknown cause, which is mainly caused by nonspecific inflammation and ulcer formation of rectum and colon mucosa. The main clinical symptoms are abdominal pain, diarrhea, acute diarrhea and mucus purulent bloody stool. The course of the disease is prolonged and often recurs. Some patients may have parenteral manifestations such as joints, skin, eyes, mouth, liver and gallbladder. The diagnosis of this disease mainly depends on colonoscopy and pathological examination. Clinical types can be divided into four types: chronic recurrent type, chronic persistent type, acute explosive type and initial type. The main complications were hemorrhage, perforation, toxic Hirschsprung's disease and canceration. Traditional Chinese medicine believes that this disease belongs to the category of dysentery, diarrhea, intestinal wind and diarrhea. In terms of treatment, it advocates dialectical treatment, which is mainly divided into: the main symptoms of intestinal damp-heat syndrome are abdominal pain and diarrhea, pus and blood in stool, frequent defecation, dry mouth and bitter taste, or fever, red tongue, yellow and greasy fur and slippery pulse. Treatment: clearing intestines and eliminating dampness. Prescription: Peony Decoction. Commonly used drugs: Coptidis Rhizoma, Scutellariae Radix, Radix Paeoniae Alba, Radix Aucklandiae and Glycyrrhrizae Radix. Clinical addition and subtraction: in case of bloody stool, Sanguisorba officinalis, Agrimonia pilosa and Sophora japonica are added; If the heat enters the collaterals and bleeding persists, add water, such as Niu Jiao tablets, Radix Paeoniae Rubra, Cortex Moutan, Radix Rehmanniae and Fructus Gardeniae; Wet and turbid, greasy fur, plus Acorus gramineus, raw Coix seed and Patrinia, besides drug treatment, it is also important to pay attention to the adjustment of life for the rehabilitation of this disease. Generally, it is advisable to eat low-fiber, low-fat, digestible and nutritious foods, try to avoid unbearable or suspected unbearable foods such as milk and peanuts, quit spicy and cold stimulants, and quit smoking. People with abdominal pain and diarrhea should eat a diet with low residue, low fat and low lactose. Especially for patients with serious illness, obvious purulent stool and malnutrition, enteral nutrition plus parenteral nutrition can be used for treatment. Patients with particularly serious diseases should receive total parenteral nutrition. Patients with long-term bleeding should pay attention to iron supplementation. Keeping a happy mood and regular life, avoiding overwork, preventing intestinal infection and strengthening physical fitness can also play a certain role in preventing the onset of this disease.
6. In addition to diet control, patients with chronic diarrhea take "Yongcang Hu Ling Zhixie Capsule" for a long time, which has a very good effect on ulcerative colitis.