Oral liquid Sterilization with what equipment

The traditional method is generally used for steam sterilization with water drenching, which requires the material to be heated up to 121?℃ and kept for more than 20?min in order to kill the bacteria. Due to the moist heat sterilization heat conduction is from the outside and inside, in order to achieve this goal, there is a need for a long time heating time, including a long time on the material warming process, all the sterilization cycle generally need to be 1 ~ 1.5?h can be completed, the energy consumption is high, the efficiency is low.

Microwave sterilization of sea cucumber oral liquid is to heat the material inside and outside at the same time, the internal temperature is high, heat conduction is from the inside to the outside, the warming is uniform and rapid heating, the time is shorter, such as the use of microwave sterilization, it can be made: (1) Escherichia coli and Bacillus subtilis in the microwave field as long as the temperature is heated to 70 ℃, keep 2?min can be killed by all; (2) Wet heat bacillus subtilis fat, in the microwave field. temperature 70 ℃, keep 2min, that is killed.

Sterilization with 15kW tunnel type small microwave equipment, 50s can kill bacteria, 18kW microwave equipment 35s can kill bacteria.

Some people have done oral solution microwave sterilization test: the amount of bacteria up to 3.5 million E. coli oral solution, sealed in 1 ~ 2?ml of the ampoule, by 3 ~ 5kW power, 2450?MHz microwave role of 15?s or more, the ampoule temperature is close to 110 ℃ or so, the cell bacteria can be all killed. Staphylococcus aureus in this result is similar. Bacillus subtilis bacterial cells, the content of 60,000 ~ 80,000, the liquid temperature must reach 140 ℃, keep more than 20s to kill completely. Containing 2?000 ~ 3?000 cyanobacterial cells of oral solution, under the action of 3 ~ 4kW microwave power, the liquid temperature reaches more than 120 ℃, after 20 ~ 23s, that is completely killed.

The degree of influence on the active ingredient of the oral solution

According to foreign literature, microwave sterilization, the active ingredient of the drug will not be decomposed, with the traditional method of sterilization, the active ingredient of the drug decomposition of significant. A pharmaceutical factory in Qinhuangdao conducted a comparative test with several samples, and the results were exactly the same as those reported in the literature.

Microwave treatment of oral fluid comprehensive economic effect of the analysis

It is estimated that there are 5000 oral fluid manufacturers, microwave equipment for oral fluid sterilization less than 5% of the manufacturers. If everyone can use microwave equipment for sterilization treatment, not only can we improve the grade of the product and overcome the quality problems of oral liquid, but also save a lot of human and material resources. At present the equipment in Weihai sea cucumber oral liquid enterprise service.