Since 1 mg = 1,670 units, 800,000 units of penicillin G sodium would weigh 800,000/1670 = 480 mg = 0.48 grams.
The weight of a particular pure antibiotic product is converted to two units. Such as the second penicillin international standard product (1952) penicillin G sodium weighing 0.5998 micrograms for 1 unit, that is, 1 mg = 1670 units, then 800,000 units of penicillin G sodium weighing should be 0.48 grams. Although penicillin G sodium products are now fully available chemical or physical methods to test its content, but still widely used potency unit of expression.
By its characteristics can be divided into:
Penicillin G category: such as penicillin G potassium, penicillin G sodium, long-acting cillin ` penicillin G, peillin G, penicillin, penicillin sodium, benzylpenicillin sodium, penicillin potassium, benzylpenicillin potassium, etc..
Penicillin V: (alias: phenoxymethylpenicillin, 6-phenoxyacetamido penicillanic acid) such as penicillin V potassium, etc. (including a variety of dosage forms).
Enzyme-resistant penicillin: such as benzathine penicillin (new penicillin II), chlorazolyl penicillin and so on.
Ampicillins: e.g., ampicillin, amoxicillin, etc.
Extended information:
p>Before the application of penicillin, in addition to the skin test, but also pay attention to the following points:
1) to the rescue equipment of the regular medical unit to inject penicillin, in case of allergic reactions, can be timely and effective rescue treatment. At any time during the injection process dizziness and panic, sweating, breathing difficulties and other discomforts, you should immediately tell the doctor and nurse.
2) After the penicillin injection, observe the hospital for at least 20 minutes without discomfort before leaving.
3) Don't apply penicillin when you are extremely hungry, in order to prevent the body's tolerance to the drug from decreasing when you are fasting, and induce adverse reactions such as fainting from the needle.
4) Do not give two injections too close to each other, 4 to 6 hours is good. Intravenous drip penicillin, the beginning of the speed should not be too fast, not more than 40 drops per minute is appropriate, observe 10 to 20 minutes without adverse reactions and then adjust the infusion rate.
5) If there is a history of penicillin injection on the same day, and dizziness, panic, sweating, dyspnea and other discomforts occur at home, it should be sent to the hospital in time for treatment.
2, dosage
1) Adults commonly used: ① intramuscular injection, 800,000 to 2 million U per day, administered in 3 to 4 times; ② intravenous drip, 2 million to 10 million U per day, administered in 2 to 4 times.
2) Pediatric dosage: ① Intramuscular injection, 25,000U/kg, l times every 12 hours. ② Intravenous administration, 50 to 200 thousand U/kg daily, divided into 2 to 4 times.
3) Neonatal dose: 1 time 50,000 U/kg, intramuscular injection or intravenous administration, every 12 hours in the first week of life, >every 8 hours for 7 days, and every 6 hours for severe infections.
4) Dosage for preterm infants: 30,000 U/kg every l2 hours in the first week, l every 8 hours at 2 to 4 weeks, and every 6 hours thereafter.
Baidu Encyclopedia-Penicillin