∵ ⊙ O is tangent to ⊙ C, ⊙ O is tangent to ⊙ D, AB is the tangent to ⊙ O,
∴∠DAB = ∠AB = 90 ° ∠ADE = 90 °,
∴AD∥BC,
∵AD = BC,<
∴Quadrilateral ABCD is a parallelogram,
∴Quadrilateral ABCD is a rectangle,
∴CD=AB=400mm,
∵OF⊥CD,
∵OD=OC,
∴CE=200mm,
Set the radius of the large circular workpiece to x, OC=x+ 50, then OE=x-50 (mm),
∵OC2=OE2+EC2,
that is, (x+50)2=(x-50)2+40000,
Solve: x=200,
∴the diameter of the large circular workpiece is 400mm,
Written in scientific notation, it can be written as: 4×102.<
So choose D.