Biological drugs are characterized by high pharmacological activity, small side effects and high nutritional value. Biological drugs mainly include protein, nucleic acids, sugars, lipids and so on. Animal raw materials obtained by immunization, microorganisms or other cell raw materials obtained by changing gene structure, etc. These substances are composed of amino acids, nucleotides, monosaccharides and fatty acids. It is not only harmless to human body, but also an important nutrient.
Extended data
Application of biopharmaceuticals in DNA vaccine for type I diabetes mellitus
The DNA vaccine based on B7- 1-PE40KDEL exotoxin fusion gene has recently obtained the international "tripartite" invention patent authorization. This achievement is an original achievement with completely independent intellectual property rights, and it is also the first international "tripartite" invention patent authorization in the field of new therapeutic DNA vaccine in China, that is, this achievement will be patented in the three largest markets in the world (the United States, the European Union and Japan).
Therapeutic DNA vaccine has strong specificity, definite curative effect, good safety and low production cost, and now it has become another new strategic commanding point in the global biopharmaceutical industry after monoclonal antibody drugs. According to reports, the DNA vaccine can effectively prevent and treat type I diabetes in previous animal experiments, correct the disordered cellular and humoral immune response of type I diabetes, repair damaged islet β cells and restore insulin secretion.
The vaccine only needs subcutaneous or intramuscular injection once, which can effectively maintain the curative effect for nearly one month, greatly improve the compliance of DNA vaccine and avoid the trouble of patients taking medicine every day.
Baidu encyclopedia-biology pharmacy
People's Daily Online-type I diabetes DNA vaccine has won the international "tripartite" invention patent.