What are the sterilization environment and use characteristics of ethylene oxide sterilizer?

? Ethylene oxide sterilizer is a device that uses ethylene oxide gas as a sterilizing agent. It can kill various microorganisms at room temperature, including bacillus, tuberculosis bacillus, bacteria, viruses, fungi and so on.

Ethylene oxide sterilizer is mainly divided into 3 categories:

Large-scale ethylene oxide sterilizer: generally used for the sterilization of a large number of items, the dosage of 0.8kg/m ~ 1.2kg/m, at 55 ℃ ~ 60 ℃ under the action of 6h.

Medium-sized ethylene oxide sterilizer: generally used for single-use diagnostic and therapeutic supplies sterilization. Advantages: well-equipped, high degree of automation, available pure ethylene oxide or ethylene oxide and carbon dioxide gas mixture. General requirements for sterilization conditions: concentration of 800 mg / L ~ 1000mg / L, temperature 55 ℃ ~ 60 ℃, relative humidity of 60% ~ 80%, the role of time 6 h. The completion of the sterilization needs to be vacuumed, sterilized items are commonly used through the ethylene oxide of the plastic film sealed packaging.

Small ethylene oxide sterilizer: used in the medical and health sector to deal with a small number of medical devices and supplies, there are 100% pure ethylene oxide or ethylene oxide and carbon dioxide gas mixture. It can automatically vacuum, automatically add drugs, automatically adjust the temperature and relative humidity, and can automatically control the sterilization time.

Environmental requirements for sterilization:

Items to be sterilized must be thoroughly cleaned, and cannot be cleaned with saline, and there can be no water droplets on the sterilized items, so as not to cause dilution and hydrolysis of ethylene oxide. Ethylene oxide can be used for sterilization of almost all medical supplies, but not for sterilization of food, liquid, oil and grease, talcum powder and animal feed. Paper, composite dialysis paper, cloth, non-woven fabrics, ventilated rigid containers, polyethylene and other packaging materials can be sterilized with ethylene oxide; metal foil, PVC, cellophane, nylon, polyester, polyvinylidene chloride, polyvinylidene chloride, polypropylene that can not be ventilated can not be sterilized with ethylene oxide.

Use characteristics:

1. Within a certain range, the temperature rises and the concentration increases, which can shorten the sterilization time. In the use of ethylene oxide sterilization must be a reasonable choice of temperature, concentration and time parameters.

2. Control the relative humidity of the sterilization environment and the water content of the items:? The water content of the bacteria itself and the water content of the sterilized items have a significant impact on the sterilization effect of ethylene oxide. In general, the relative humidity of 60% ~ 80% is the best. Too little water content, affecting the penetration of ethylene oxide and alkylation of ethylene oxide, reducing its bactericidal ability; too much water content, ethylene oxide is diluted and hydrolyzed, also affecting the sterilization effect. In order to achieve the ideal level of humidity, the first step is to sterilize the material must be pre-humidified, generally required to sterilize the material placed in 50% relative humidity environmental conditions for at least 2h or more; the second step can be used to humidify the device to ensure that the cabinet indoor ideal humidity level.

3. Pay attention to the bacterium outside the protection of the effect of sterilization: the more organic matter contained on the surface of the bacterium, the more difficult to kill; organic matter can not only affect the penetration of ethylene oxide, but also consume part of the ethylene oxide. Microorganisms in inorganic salts or organic crystals are difficult to kill with ethylene oxide. Therefore, before ethylene oxide sterilization, the items must be fully cleaned of organic and inorganic dirt to ensure the success of sterilization.