Entrepreneurs are valuable human resources in society and play an important role in developing China's socialist market economy, promoting the development of social productive forces, enhancing China's comprehensive national strength and promoting stability and unity. Since the reform and opening up, entrepreneurs have always been in the front line of opportunities and challenges. They made achievements and paid the price. They need to pay attention to many problems, and have made a lot of efforts to promote economic development, but they seldom care about their own health. Some of them fell to their jobs, some insisted on working because of illness, and some were in a sub-health state for a long time because of lack of health knowledge. The health problem of entrepreneurs has become a new topic of social development and health work in China. Health problems are not only very important for entrepreneurs, but also an important factor affecting the development of enterprises. The health problem of enterprise groups has always been one of the focuses of health work in China, and the state has done a lot of work to ensure the health of enterprise groups. However, with the establishment of socialist market economy in China, many changes have taken place in social strata and enterprise conditions, and great reforms have taken place in health and social security policies. This situation makes the original working mechanism and measures can not meet the needs of today's enterprise health protection. In order to arouse the society's concern and support for the health protection of enterprises, entrepreneurs and workers, and to explore a new working mechanism for providing quality services for the health protection of enterprises, in 2006 10, the Entrepreneurs Association of china enterprise confederation and China and the China Medical Foundation implemented the spirit of General Secretary Theory of Three Represents and Jiang's instruction of "serving enterprises and entrepreneurs better".