1949 was handed down by family, and he sat in the clinic with his father (Mr. Shi Yiren, a famous old Chinese medicine doctor). He studied in the special department of the former Central Affiliated High School of Traditional Chinese Medicine and later changed to Nanjing School of Traditional Chinese Medicine. 195 1 year graduated, 1952 obtained the qualification of Chinese medicine practitioner in Nanjing, and officially practiced medicine. From 65438 to 0953, I studied western medicine in the Medical College of Shandong University for five years, and stayed in the internal medicine department of the affiliated hospital of Shandong University after graduation. From 65438 to 0959, he was transferred from the Central Ministry of Health to the Institute of Traditional Chinese Medicine to engage in clinical medical treatment, scientific research and teaching of traditional Chinese medicine. He has been engaged in clinical research in the departments of infection, gastroenterology and nephrology of Xiyuan Hospital.
He has been a doctor for more than 40 years and published more than 200 academic papers, including Treatise on Febrile Diseases Series, Essentials of Syndrome Differentiation and Treatment of Exogenous Fever, Essentials of Syndrome Differentiation and Treatment of Nephritis in Traditional Chinese Medicine, Outline of Diagnosis and Treatment of Traditional Chinese Medicine (Japanese Edition), and Shi's Nephrology. He also participated in the compilation of Practical Internal Medicine of Traditional Chinese Medicine. Presided over the professional work of kidney disease in traditional Chinese medicine. Good at Chinese medicine, gynecology, pediatrics, etc. It is especially suitable for fever, spleen and stomach diseases and nephropathy. In particular, the graduate department Clinical Laboratory of Chinese Academy of Traditional Chinese Medicine, established under his leadership, takes the Department of Nephrology of Xiyuan Hospital as its clinical research base, and is one of the earliest units in China to carry out research on the treatment of kidney diseases with integrated traditional Chinese and western medicine. For more than 30 years, we have always insisted on highlighting the characteristics of traditional Chinese medicine, giving full play to the advantages of traditional Chinese medicine in treating kidney diseases, trying to absorb the latest scientific research achievements of modern science and technology, taking the road of combining traditional Chinese and western medicine, and constantly exploring and summarizing, forming a set of syndrome differentiation and treatment system, which has played a positive role in promoting the development and growth of kidney disease research in traditional Chinese medicine. This laboratory has become one of the few most influential units in the research of kidney disease in Chinese medicine, and it is also the clinical pharmacological base of kidney disease research in the Ministry of Health. He has been to Mexico, Belgium, Netherlands, Japan, Thailand, Germany, Hongkong, Taiwan Province Province, Macau and other places to give lectures and medical activities, and has been welcomed by friends from all over the world.
He has made great achievements in the academic field and kept improving in clinical medicine. He studied Chinese medicine in his early years, and then he began to study western medicine again. He has devoted himself to the research of integrated traditional Chinese and western medicine for a long time, especially on infectious diseases and nephropathy, and put forward many creative academic viewpoints, which have important guiding significance for improving clinical efficacy.
For example, in the study of infectious diseases, the typhoid and febrile diseases of traditional Chinese medicine are discussed theoretically. It is the first time to put forward the viewpoint of the rise and fall of yin and yang, and explain the development and change of acute fever with the rise and fall of yin and yang, and reasonably explain Jue Yin disease which is considered as an eternal mystery and difficult to explore in Treatise on Febrile Diseases. It is considered that Jue Yin disease is heat syncope caused by the decline of Yin and Yang, which is equivalent to infectious syncope in modern medicine. According to the treatment principle of heat syncope, it was used to treat coma patients with toxic bacillary dysentery, which saved their lives in time and achieved good results.
For another example, in the research of nephropathy, he mainly studied the theory and practice of chronic glomerulonephritis and chronic renal failure in traditional Chinese medicine, with the aim of applying the experience of traditional Chinese medicine to the disease research of modern medicine, thus generating new theories to guide clinic and improve curative effect.
Participated in more than ten national academic seminars on Chinese medicine nephropathy and integrated traditional Chinese and western medicine, and exchanged experiences in treating chronic nephritis and chronic renal failure. In order to improve Chinese medicine's understanding of this disease, according to his clinical experience, he put forward a syndrome differentiation and classification scheme with deficiency of positive energy as the main indication and excess of evil energy as the clamp treatment, which was regarded as a unified syndrome differentiation scheme and curative effect judgment standard in China and proved to be more in line with clinical practice. He also proposed for the first time that we should pay attention to the deficiency of both qi and yin in syndrome differentiation, which is helpful to improve the curative effect. These have been recognized and praised by fellow travelers.
He presided over a number of scientific research projects, and he presided over the national "Seventh Five-Year Plan" key project "Clinical and Experimental Research on Kidney Deficiency Syndrome of Chronic Nephritis". In practice, he found that Yiqi Yangyin prescription can protect and restore renal function and promote the reduction or disappearance of proteinuria; Zishen Huayu recipe has the function of treating and eliminating nephritis hematuria. Its series of new drugs such as Baoshen Granule, Zishen Zhixue Tablet, Shen Yan Ⅱ Granule, Shenshuai Capsule and Yishen Quzhuo Oral Liquid have obvious curative effects on chronic nephritis and chronic renal failure.
In academic research, due to his in-depth practice and good thinking, his exploration of problems is always nuanced, repeatedly compared and to the point. The viewpoints put forward are unconventional and never follow the trend, but further deepen their own theories in practice. For example, for exogenous fever, it has always advocated the confluence of cold and heat, thinking that the two objects are the same, both of which are acute infectious or infectious diseases, but the symptoms at the beginning are different from those on the cold and heat side, and the future outcome and course of disease are roughly the same. Because the ancients could not clearly distinguish between various infectious diseases and different processes of infectious diseases, they thought it was the stage of solar disease at first, and then some sun spread to Yangming, some sun spread to at least Yang, and some sun directly spread to Taiyin or Shaoyin or Jueyin. The six-channel syndrome differentiation used is different from that of Wei Qi and Xue Ying, but the essence is the same, so he has the theory of the identity of the six-channel syndrome differentiation with that of Wei Qi, Xue Ying and Sanjiao.
He advocates the combination of disease differentiation and syndrome differentiation, especially the dynamic change of syndrome, which is another academic thought of his. He believes that the treatment of infectious diseases, infectious diseases and miscellaneous diseases in internal medicine should adopt the method of combining disease differentiation with syndrome differentiation. Every disease has its particularity, and syndromes have their commonness. According to the law of disease development, syndromes are constantly changing. Therefore, only by paying attention to the dynamic changes of syndrome differentiation and treatment can we reflect the characteristics of individualized treatment and the advantages of traditional Chinese medicine treatment. For example, in the diagnosis and treatment of chronic nephritis, it is considered that although the course of disease is very long, there is also a transformation of syndrome types. Deficiency of spleen and kidney or deficiency of liver and kidney yin can be transformed into deficiency of both qi and yin. 1980 put forward the pathogenesis and treatment of this syndrome for the first time, and then more and more colleagues unanimously recognized it.
In the treatment of chronic diseases, Shi Zhensheng emphasized the need to grasp the relationship between good and evil, especially those diseases in which good and evil are manifested in vain. Such as chronic renal failure, when the condition is stable, we should give priority to strengthening the body resistance, but we should also give consideration to evil and excess; When evil is prominent, the top priority should be to eliminate it. In most cases, the pathogenic factors of chronic renal failure are reversible aggravating factors, such as infection, heart failure, insufficient blood volume and electrolyte disorder. Controlling these factors can often turn the disease into safety and tend to be stable.
He also stressed that the treatment of acute diseases should prevent its transformation. There are two meanings: first, early treatment to avoid biochemical syndrome; The second is to protect its shortcomings. This is of great significance to the treatment of acute fever, which can control infection, prevent complications and promote early recovery. In the treatment of chronic diseases, due to the correlation between the five zang-organs, "deficiency of pathogenic factors will damage the yin, and the injury of the five zang-organs will lead to poverty of the kidney", so it is necessary to emphasize the treatment of chronic diseases from the kidney to obtain better curative effect. Such as toxic encephalopathy and motor neuron diseases caused by carbon monoxide, are often cured by tonifying kidney and promoting blood circulation; The treatment of chronic asthmatic bronchitis in the elderly is often effective in tonifying kidney and absorbing qi; For chronic ulcerative colitis and intestinal dysfunction that cannot be cured for a long time, it is often effective to tonify kidney and astringent essence; The treatment of senile prostatic hypertrophy is often effective by tonifying kidney and promoting diuresis; The treatment of chronic nephritis is mainly to tonify the kidney (warming the kidney and promoting diuresis, warming the kidney and strengthening the spleen, nourishing the kidney and clearing away profits, nourishing the liver, nourishing the kidney and benefiting qi, nourishing the kidney and clearing heat, etc.). ), and achieved remarkable results.
He is famous not only for his unique academic achievements, but also for his noble personality. Especially in academic research, he is tireless and extremely rigorous. It has trained hundreds of TCM kidney disease backbones and more than 200 advanced students, and often held lectures and medical activities all over the country, which has made great contributions to solving the shortage of TCM successors and cultivating TCM talents, especially TCM kidney disease talents. In his lectures, he always treats academic problems with a realistic attitude, convinces people by reasoning, and never seeks fame and reputation. At the same time, I don't hold a portal view, learn from others, and often use my own clinical practice to verify it. On the basis of verification, he constantly enriched and developed.
When teaching students, he always sets an example and acts as a teacher. He often warns students not only to master the knowledge of traditional Chinese medicine, but also to master the necessary knowledge of western medicine and other disciplines. On the basis of the combination of traditional Chinese and western medicine, he should better excavate and systematically sort out the theory of traditional Chinese medicine, and use modern experimental means and methods to verify and develop the theory in practice, and then practice under the guidance of the theory. This can not only make the theory not vague, but also make the practice not blind. Professor Shi Zhensheng set an example by teaching and educating people, and trained 14 doctoral students, 14 master students and dozens of international students. Graduate students have become the technical backbone in the field of traditional Chinese medicine in China, and many of them have also taken on the heavy responsibility of the heads of national, ministerial and bureau-level kidney disease research projects.
Because of his profound theoretical foundation of traditional Chinese medicine, exquisite medical technology and rich clinical experience, doctors at home and abroad are always in an endless stream. He received patients warmly and treated them seriously, and also served as the health care task of national leaders for a long time. For the letter of seeking medical advice, each letter is written in person, and it will never be perfunctory or written by others. His earnest attitude is really admirable.