Acute toxicity: LD50309mg/kg (taken orally by rats); 214mg/kg (taken orally by mice)
Carcinogenicity: After 4,4'-diaminobiphenyl enters the internal environment, the target organ is the bladder. The lowest subcutaneous toxic dose of mice was 8mg/kg(35 weeks, intermittent), which caused cancer; The lowest oral toxic dose of rats is 4500 mg/kg (intermittent for 30 days), which is carcinogenic. The lowest toxic concentration for human inhalation is 18mg/m3× 13 years (intermittent) carcinogenic positive. Respiratory system protection: Wear a gas mask when the concentration in the air is high. Self-contained breathing apparatus should be worn during emergency rescue or escape.
Eye protection: Wear safety glasses.
Protective clothing: wear tight-sleeved overalls and long rubber shoes.
Hand protection: wear rubber gloves.
Others: Smoking and eating are prohibited in the workplace. Change work clothes in time. Don't drink before and after work, take a bath with warm water. Conduct pre-employment and regular physical examination. Skin contact: Take off contaminated clothes immediately and rinse thoroughly with soapy water and clean water.
Eye contact: Lift the eyelid immediately and rinse with plenty of flowing water or normal saline.
Inhalation: leave the scene quickly and go to a place with fresh air. Oxygen is given when breathing is difficult. When breathing stops, give artificial respiration immediately. See a doctor.
Intake: gargle, drink water, gastric lavage and then take activated carbon orally, and then give catharsis. See a doctor.
Fire extinguishing methods: misty water, foam, carbon dioxide, dry powder and sand. On-site emergency monitoring method
Rapid Colorimetry of Harmful Substances in the Air of Chemical Enterprises, Chemical Industry Press.
Laboratory monitoring method
High Performance Liquid Chromatography (China National Environmental Monitoring Center, Water Quality)
Handbook of Chromatography/Mass Spectrometry for Experimental Analysis and Evaluation of Solid Waste translated by China National Environmental Monitoring Center, etc.
Standard Test Method for Spectrophotometric Determination of Water and Wastewater 15 Edition