A study done by the Affiliated Hospital of Copenhagen University counted 600,000 Danmai people. They found that people with overweight body mass index (height and body mass index) live longer than those with normal body mass index, and some people with normal body mass index will develop obesity-related metabolic diseases, which indicates that the relationship between weight, health and life expectancy may not be absolutely related.
Another study by the University of Copenhagen was published in PLOS Synthesis. Because of hyperlipidemia, it is easy to suffer from type 2 diabetes, which leads to the accumulation of fat in the heart and liver. In the past, people agreed that overweight and obesity would increase the risk of diabetes and cardiovascular diseases, but 65,438+05-20% obese people did not have these health problems. Researchers tried to understand the reasons why these obese people stayed healthy.
They studied the genetic maps of 60 obese people, 28 of whom had no metabolic diseases caused by obesity.
However, they found that there are three genes related to the utilization of fat in the body, and the expression of these three genes will determine the storage or metabolism of fat in the body, which seems to explain that there are also gene expression variables in the correlation between obese people and cardiovascular diseases.
This discovery may be applied to the diagnosis of weight management and metabolic diseases, drug development and even the development of gene-targeted drugs abroad, but the researchers said that this research result should not be an excuse for unbalanced diet and inactivity. After all, besides weight control, a healthy lifestyle still has an important impact on the body. Don't neglect diet and exercise just because you think that obesity doesn't necessarily lead to these diseases.
Reference 1. The increase in body mass index is associated with the lowest risk of death 2. Anne Tabby? Rg-Hansen et al. The change of body mass index is related to the lowest mortality rate in Denmark. 1976-20 13 JAMA. 20 16; 315 (18) 3. The interosseous genes such as Haja Kadarmideen co-express Neorks beeen, which metabolizes healthy and unhealthy obese individuals PLOS-(2013) August 19.
Subject: body mass index, gene, type 2 diabetes, obesity