The fertilized eggs of IVF are transplanted into the body at the 8-cell stage on the third day or the blastocyst stage of 5-6 days. It would be a miracle if human beings could mature embryos in vitro. Repeated abortion (or embryo termination) may mean that the embryo itself may be unhealthy, or the conditions in the uterus are not conducive to its growth. At present, it is impossible for us to know all the factors that lead to embryo arrest.
Chromosome problems of both partners or fertilized eggs account for about 10% of all embryo terminations. Secondly, abnormal uterine morphology is often a factor of recurrent abortion, accounting for about 30%. Normal endocrine environment is often the chief culprit of recurrent abortion, including abnormal luteal development, abnormal thyroid function, abnormal adrenal function (abnormal blood sugar), abnormal pituitary and ovarian hormones. Repeated abortion caused by chromosomal abnormalities is a natural choice. This selection mechanism will eliminate bad embryos, so that healthy and high-quality genes of human beings can be carried forward and propagated.
Repeated abortion caused by this factor is incurable. We choose to let nature take its course and do not advocate abortion treatment. Repeated abortion caused by abnormal uterine morphology can be corrected by surgery in some cases, but not in other cases. Repeated abortion caused by infection can be treated more. Repeated abortion caused by endocrine abnormalities can be adjusted. For immune factors, active immunotherapy with Freund's lymphocytes and passive therapy with intravenous immunoglobulin can be used. According to reports, the effective rate is about 70% ~ 80%. Recurrent abortion is still a stubborn and intractable disease, and sometimes we are helpless. But active exploration and treatment sometimes produce unexpected results. With the continuous exploration of scientists, people will gradually conquer it.