Brain and intestine health

Intestine is the second brain and the most sensitive organ of human body. At present, the pressure of work or life is too great, and people are emotionally nervous, anxious, depressed and irritable. It is easy to cause autonomic nerve dysfunction, leading to slow gastrointestinal peristalsis, reduced secretion of digestive juice, and symptoms such as loss of appetite, indigestion and constipation. On the contrary, when there are various lesions in the intestine, it will also lead to the above emotional changes in patients. So intestinal health will affect your mood for the following reasons.

Doctor. Intestinal health affects our mood from three aspects, and intestinal flora imbalance affects our mood. Intestinal bacteria are rich and diverse, which are mutually beneficial to the host and affect the health of the host. Studies have shown that intestinal flora can affect the function of intestinal brain axis and cause nervous system diseases. Intestinal brain axis is a two-way reaction system, which integrates the functions of brain and intestine through the central nervous system and enteric nervous system.

Neurotransmitters produced by harmful intestinal flora act on the central nervous system through the intestine and vagus nerve, regulating the release of brain-derived neurotrophic factor. These neurotrophic factors act on peripheral and central nerve cells at the same time, and are closely related to mood-related dopaminergic, cholinergic and 5- hydroxytryptamine neurons. When the intestinal flora is out of balance, the intestine will produce a series of harmful neurotransmitters, which will affect the central nervous system and cause emotional changes of depression.

The influence of intestinal inflammation on mood, research shows that under the acute stress response of intestinal inflammation, the expressions of brain-derived neurotrophic factor and phosphorylated cyclic adenosine monophosphate effector protein in the hippocampus and frontal cortex of the brain are significantly reduced. The decrease of these neurotransmitters can lead to emotional changes, such as depression and anxiety. Why does intestinal health affect people's mood? Because intestinal diseases themselves are psychosomatic diseases, and the connection between human brain and intestine is very close.

New knowledge "brain-gut axis" We know that intestinal microorganisms exist in our intestinal microbial flora, and this special microorganism is not only a long-term resident of the intestine, but also plays a very important role in nutrient absorption, metabolism, autoimmune, growth and development and various diseases of the intestine and even the whole human body. Therefore, through continuous research, scientists in China named the brain-gut axis as a special mechanism that intestinal flora can affect human function and even brain structure and function.