It is reported that BCR/abl fusion gene is positive in some normal people, but they have no hematological diseases such as chronic myeloid leukemia. There are two main considerations: ① Although there are BCR/abl positive fusion gene fragments in the body, the number is generally small, which can not reach the therapeutic level and will be quickly eliminated by the in-vivo monitoring system. ② The life activities of human cells are very complicated, and the transmission of life signals has both * * * and personality. Although BCR/abl fusion gene can promote granulocyte proliferation and inhibit granulocyte apoptosis, it still depends on the influence and regulation of tumor suppressor genes.