At present, serum creatinine (basically unaffected by diet, high metabolism and other extrarenal factors) combined with the patient's age and weight is the most accurate index to evaluate glomerular function. Urea nitrogen is often influenced by many factors and cannot be used to evaluate renal function. For example, eat high-protein foods-meat, fish, eggs and so on. , high fever, septicemia, gastrointestinal bleeding, etc. Can increase urea nitrogen. It is worth noting that the normal value of serum creatinine is 43 ~106 μ mol/L. When the injury is above 70% ~ 75%, the serum creatinine will increase rapidly. Therefore, we can use ECT (endogenous creatinine clearance rate) to further understand glomerular function, and its normal value is 80 ~ 1.20 ml/min. If the measured value is 70 ~ 5 ~ 0ml/min, the renal function will decrease slightly, 50 ~ 30ml/min will decrease moderately and less than 30ml/min will decrease severely.10 ~ 5ml/min is the end-stage renal failure, and 5 ~ 0ml/min is the end-stage renal failure. In addition, routine urine examination is a common index to determine renal lesions. Negative urine routine does not mean that renal function is not impaired, such as end-stage renal failure and end-stage renal failure, which may occur. Because kidney function is extremely damaged, it is difficult to filter urine, let alone protein.
To sum up, the most accurate indexes to check renal function are serum creatinine and ECT, but it should also be combined with medical history, clinical manifestations, urine test and renal pathological examination to make an accurate judgment on renal lesions and their degree.