canine parvovirus disease
This is a strong intestinal infectious disease in dogs, which can cause a lot of vomiting, diarrhea (bloody stool), loss of appetite, high fever and a lot of dehydration, leading to the death of puppies and elderly dogs.
The source of canine parvovirus is still unknown. Because there is no medicine for parvovirus, it only needs symptomatic treatment. Doing a good job in environmental sanitation and vaccination will help prevent the spread of this disease. In addition, dogs must be injected with six vaccines on time to prevent it!
[Clinical manifestations]
Dogs developed somatic symptoms within 3- 14 days after exposure to parvovirus, with an average onset time of 5-7 days. Clinical symptoms include loss of appetite, depression, fever, vomiting and diarrhea. Adult dogs don't necessarily have fever at first, but often have loss of appetite, depression, vomiting and diarrhea (after 24 hours), and sometimes they repeatedly vomit violently, and their feces are thin, sprayed or bloody. The mortality rate of adult dogs is 2-3%. The death rate of puppies (shock caused by high dehydration) is 25-50%. Therefore, early rehydration is the key to treatment.
Dogs infected with parvovirus can be divided into enteritis type and myocarditis type.
Enteritis type: the incubation period of natural infection is 7 days to 14 days, with initial fever, body temperature above 40℃, listlessness, no eating and vomiting. At first, the vomit was food, and later it was a viscous yellow-green liquid. Diarrhea began one day after onset. At the beginning of the disease, the feces are thin and mushy. With the development of the disease, the feces are ketchup-colored or coffee-colored, with a foul smell, and the frequency of defecation is uncertain, with symptoms of first urgency and then heaviness. After hematochezia, the sick dog showed eye drops, dry nose, general weakness, obvious weight loss, pallor of conjunctiva and oral mucosa, and severe anemia symptoms. If the disease is not treated in time, it can cause toxin absorption and poisoning of intestinal contents until death by shock.
Myocarditis type: more common in puppies around 40 days old. The sick dogs have no obvious clinical symptoms, and some of them suddenly have difficulty breathing and heart failure, and die in a short time; Some sick dogs died after mild diarrhea. The newborn puppies infected with parvovirus have heart disease, which can quickly destroy the myocardial cells of puppies. Then, asthma, cyanosis of oral mucosa and skin, and sometimes sudden failure and death are the only symptoms of this disease in puppies. Due to permanent myocardial injury, tolerant puppies can still die of the disease weeks or even months after infection.
[Transmission of Parvovirus]
Parvovirus can be transmitted through feces. Parvovirus disease mostly occurs in parks, dog shows, kennels, pet hospitals and other places where dogs gather. Although people will not be infected with parvovirus, shoes contaminated by feces also play a role in spreading diseases.
Dogs that have not been vaccinated may get sick once they are exposed to parvovirus. This virus can withstand high temperature and survive in soil and cages for a long time. Once infected with parvovirus, it is difficult to remove it.
[Diagnosis of Parvovirus]
There are many reasons why dogs vomit and diarrhea. The diagnosis of parvovirus is usually indirect exclusion. According to clinical symptoms, brown and tomato-colored blood has a special odor. Blood phase changes, red blood cells, hemoglobin and hematocrit decrease, and white blood cells are not higher than daily values? In the case of secondary bacterial infection, the specific diagnosis method can make the final diagnosis. Now a diagnostic reagent basin has been produced, which can detect the virus in feces.
After dogs were infected with parvovirus, the number of white blood cells decreased (down to 5000 /mm3), which is not enough to prove that dogs have parvovirus disease. But when the dog's white blood cell count is less than 2000/mm3, the dog's life is in danger.
[Treatment of Parvovirus]
There is no best way to treat parvovirus. Most veterinarians take supportive therapy. For example, intravenous infusion or electrolyte supplementation can relieve dehydration, drugs can relieve intestinal spasm, and antibiotics can prevent secondary infection. Unfortunately, there is no drug to kill parvovirus in the body at present. A healthy dog can get lifelong immunity.
The key to save the sick dog is to insist on infusion treatment for 3-5 days, during which the sick dog is forbidden to fast and drink water. When the sick dog stopped vomiting for 48 hours, he slowly resumed his diet. Most dogs can be cured as long as doctors treat them properly and their owners take good care of them.
Try "Wu Bai Decoction" treatment. Received excellent curative effect, which is introduced as follows.
Prescription Pulsatilla 15g, Mume 15g, Coptidis Rhizoma 5g, Cortex Phellodendri 5g, Radix Curcumae 10g, and Fructus Chebulae 10g.
Usage: add water 1000 g to the top, fry for several times, and take the soup until it is warm, one dose a day. If the sick dog vomits too violently, metoclopramide injection can be injected about 2 hours before taking it; If the sick dog is seriously dehydrated, it should be supplemented with infusion treatment. From the symptoms, the prescription of canine parvovirus enteritis is caused by heat toxin accumulating in gastrointestinal tract and invading blood. Pulsatilla chinensis can clear blood, divide water, clear heat, stop bleeding and stop dysentery; Yujin breaks blood stasis and promotes qi circulation, relieving gastrointestinal stasis and heat; These two drugs are the main drugs. Coptidis Rhizoma and Cortex Phellodendri are supplemented by clearing heat and drying dampness; Mume and terminalia chebula are adjuvant drugs for nourishing blood, astringing yin and preventing collapse. This prescription has the effects of clearing heat, removing blood stasis, stopping dysentery and astringing yin, and is very suitable for treating canine parvovirus enteritis.
This prescription was used to treat 15 dog owners 18 sick dogs, and 15 cases were cured, most of which were cured by 3-5 doses.
In addition, the disease is mainly prevention. Canine parvovirus disease can be treated with special therapy at an early stage. At present, many domestic scientific research units have developed monoclonal antibodies and antiserum against canine parvovirus, which can be used in clinic and achieved good therapeutic effects. Rehydration, hemostasis, antiemesis and prevention of secondary infection. Available sugar salt water; Hemostasis, vitamin K 1, vitamin k3; Metoclopramide; Gentamicin, kanamycin and sulfonamides, symptomatic treatment. Blood transfusion therapy also has a good therapeutic effect on this disease.
This is the information found on the Internet.
Two red VIPs of my family died in the hospital. I think we can only rely on our own strength.
My friend also bought a little red expensive just now. He also heard a lot about the hospital and was afraid to take it to the hospital. I've been studying this matter recently. I said help me, and he said yes. I might as well try when I died in the hospital, so I'm trying to treat it. The following is my treatment process.
On the first day, the dog was very weak. Lying in the nest, refusing to move, not eating or drinking, forcing him to feed, he vomited.
My treatment:
1, oral aspirin to stop vomiting and diarrhea (water pressure 1 time)
2, subcutaneous injection of energy mixture 0.2 ml (dog 1 kg, already very thin) for nutrition.
3, half an hour oral amoxicillin for children (half a pack, a small amount of warm water brewing, syringe filling) anti-inflammatory.
4. Subcutaneous injection of micro monoclonal antibody (1 day 1 time). My friend went to the hospital to buy 2 yuan first, and Taobao sent 5 yuan. 1 piece is only 22 pieces, 80 pieces are sold in pet hospitals and 200 pieces are sold in some hospitals.
Once every 6 hours on average.
It was excreted the next day, still watery. Continue the above therapy, 12 hours without diarrhea or vomiting.
In addition to drinking medicine, I bought dog milk and rice flour to make water (which can be pumped up with a syringe).
On the third day, the soft stool (which has a shape but is completely scattered when squeezed) has a desire to eat, but it still doesn't want to eat after smelling it. Continue to force irrigation (dog milk powder+rice flour)
Today is the third day. My friend is going to put the dog in my house so that I can continue my treatment and try my best to help it recover during the Qingming period. My family has a chihuahua. I asked my wife to send it to her home and let her mother take care of it. There's another friend, Bomei. Go home and let me take care of him. Every week 1 he will come to get it, but he can't neglect it. . I just bought some fences for isolation. Bought disposable gloves.
In the evening, his master will send him to my home for further treatment. . . Show everyone the little guy's PP at night. Ha ha. .
I don't think it's terrible to be small, as long as we know what causes it (enteritis is usually much smaller, with diarrhea and vomiting). I think everything can be learned easily except intravenous injection.
Baidu knows ID: September.
/question/325662 193.html？ fr=im 100400
My family is a small professional family. There are seven dogs in my family. Two little people who were sent to hospital for treatment died. So it's very small now. They are all treated at home.
On the contrary, all the people who received treatment at home survived.
Tiny is not really scary. As long as we find out earlier. Control it. It can usually be cured.
My dog found it early, so it was better controlled. Because we no longer trust the doctors in pet shops, we all insist on treating in our own homes. Although it was painful to watch it develop, we persisted.
In fact, being small is really not terrible, and sometimes it is inevitable to draw blood and vomit blood, so parents of dogs should not worry too much, and the pressure in their hearts should not be too heavy, so the dogs will be fine.
Basically, some drugs used are anti-inflammatory, antiemetic, antidiarrheal, hemostatic, gastrointestinal regulator and serum. I must be used once every hour or two for fear of conflict between drugs. Chinese medicine can be continuously fed for two or three hours every day.
At present, there are still two little Teddy boys receiving treatment at home. One just got sick and the other was on the fifth day. Basically, the recovery process has begun. In fact, my dogs are in good condition when they are young, and there is no serious dehydration or massive bleeding. Generally, they will be fine in five days. Some dogs may take a week or 65,438+00 days to get worse, so parents should cheer up. Tiny is a protracted war, and persistence is victory.
The following is a small experience of my dog being cured.
Coco and Chihuahua: It all started with vomiting. At first, I just vomited, but I didn't have diarrhea. I think something is wrong. We immediately measured it with miniature paper and confirmed that it was miniature. Because a dog just died in the hospital, we are going to treat it at home.
Highest fairway record
Day one: depressed. Vomiting twice, no diarrhea, medication: half a branch of gentamicin (it is an injection, but we drink it, basically one a day. One and a half times a day, don't feed a lot, it will have side effects, and if you eat too much, you will be deaf) 1/3 Pack of Smecta (it is antidiarrheal, although it doesn't have diarrhea. For prevention)
The next morning: I am in good spirits and have an appetite. I gave him five pieces of dog food (most doctors will tell you to cut off water and food, but that's because he gave you nutrient solution. If I cut it at home, I think my dog will starve to death before it is cured. We give it whatever it wants, and we don't force it if it doesn't want to. Of course. Generally, dogs don't want to eat when they are uncomfortable. If they want to eat, it means that the situation is not so bad, because the drugs are all hydrated with glucose, so there is no water to drink. ) I didn't throw up in the morning and had diarrhea once. The medicine is still half clear, 1/3 Smecta, half a pack of probiotics (favorite, bought online), and I went to buy serum and beat half (. So half is enough. If you can't play, you can ask the doctor who bought it for help. )
Afternoon: I have a bad spirit and an appetite. I didn't vomit or pull, but I still have to take medicine, 5 ml of Wu Bai soup (in fact, this is really good. Especially in the case of early detection, Wu Bai Decoction can preserve the intestinal mucosa of dogs and prevent bleeding. The prescription can be found online. ) or stick to Smecta of 1/3.
Evening: The spirit is not bad. I have an appetite and ate 20 pieces of dog food and some nutritional cream (if the dog has no appetite, you can buy nutritional cream online, give it some nutrition, and eat it after it is cured to increase nutrition). Finally, my stool was a little thin, and I used half a pack of probiotics, half a large one, and 5 ml of Wu Bai soup.
The third morning: I was in a bad mood, very quiet, and lost my appetite, but I didn't vomit or pull. I continue to take medicine, 5ml of Wu Bai soup, half serum and half serum.
In the afternoon, I was still in a bad mood and had no appetite. I took a black stool, and then I kept taking a jelly-like stool. Medication: 1/3 smecta, 5 ml of Chinese medicine. At night: I vomited twice, and took half a tablet of Qingda, Chinese medicine and a tablet of vitamin B6.
On the fourth day, I was depressed, lost appetite, appeared jelly excrement and often vomited. I took the medicine, one tablet of vitamin B6 10 ml of Chinese medicine, half of Qingda 1/3 smecta and half of serum. It's almost the afternoon, and the vomiting has eased. I still continue to use Chinese medicine and smecta. Vomiting at night brought a little bloodshot, but it has stopped diarrhea. Medication: Qingda half, Chinese medicine 10 ml, and glucose soaked Yunnan Baiyao (if blood drawing and hematemesis are serious, it is recommended to give hemostatic drugs such as Zhixuemin, and the effect will be better. If vomiting is serious, some metoclopramide can be prepared).
The fifth day. I'm still in good spirits in the morning. I don't vomit or pull. I ate some soft dog food mixed with egg yolk and continued to use the medicine, half of which was clear and half of which was serum and traditional Chinese medicine. Continue at noon. I'm in good shape. I don't vomit or pull. I still used medicine and Chinese medicine as in the morning.
On the sixth day, I began to defecate normally, but my spirit has not fully recovered, but it has been much better. Still have to continue to give it dog food mixed with egg yolk.
Parents must make sure that their stools are normal before they can stop taking the medicine.
Wu Bai soup for prescription:
Pulsatilla chinensis 15g, ebony 15g, coptis chinensis 5g, phellodendron amurense 5g, curcuma aromatica 10g, terminalia chebula 10g Baidu knows ID: September.
/question/325662 193.html？ fr=im 100400
My family is a small professional family. There are seven dogs in my family. Two little people who were sent to hospital for treatment died. So it's very small now. They are all treated at home.
On the contrary, all the people who received treatment at home survived.
Tiny is not really scary. As long as we find out earlier. Control it. It can usually be cured.
My dog found it early, so it was better controlled. Because we no longer trust the doctors in pet shops, we all insist on treating in our own homes. Although it was painful to watch it develop, we persisted.
In fact, being small is really not terrible, and sometimes it is inevitable to draw blood and vomit blood, so parents of dogs should not worry too much, and the pressure in their hearts should not be too heavy, so the dogs will be fine.
Basically, some drugs used are anti-inflammatory, antiemetic, antidiarrheal, hemostatic, gastrointestinal regulator and serum. I must be used once every hour or two for fear of conflict between drugs. Chinese medicine can be continuously fed for two or three hours every day.
At present, there are still two little Teddy boys receiving treatment at home. One just got sick and the other was on the fifth day. Basically, the recovery process has begun. In fact, my dogs are in good condition when they are young, and there is no serious dehydration or massive bleeding. Generally, they will be fine in five days. Some dogs may take a week or 65,438+00 days to get worse, so parents should cheer up. Tiny is a protracted war, and persistence is victory.
The following is a small experience of my dog being cured.
Coco and Chihuahua: It all started with vomiting. At first, I just vomited, but I didn't have diarrhea. I think something is wrong. We immediately measured it with miniature paper and confirmed that it was miniature. Because a dog just died in the hospital, we are going to treat it at home.
Highest fairway record
Day one: depressed. Vomiting twice, no diarrhea, medication: half a branch of gentamicin (it is an injection, but we drink it, basically one a day. One and a half times a day, don't feed a lot, it will have side effects, and if you eat too much, you will be deaf) 1/3 Pack of Smecta (it is antidiarrheal, although it doesn't have diarrhea. For prevention)
The next morning: I am in good spirits and have an appetite. I gave him five pieces of dog food (most doctors will tell you to cut off water and food, but that's because he gave you nutrient solution. If I cut it at home, I think my dog will starve to death before it is cured. We give it whatever it wants, and we don't force it if it doesn't want to. Of course. Generally, dogs don't want to eat when they are uncomfortable. If they want to eat, it means that the situation is not so bad, because the drugs are all hydrated with glucose, so there is no water to drink. ) I didn't throw up in the morning and had diarrhea once. The medicine is still half clear, 1/3 Smecta, half a pack of probiotics (favorite, bought online), and I went to buy serum and beat half (. So half is enough. If you can't play, you can ask the doctor who bought it for help. )
Afternoon: I have a bad spirit and an appetite. I didn't vomit or pull, but I still have to take medicine, 5 ml of Wu Bai soup (in fact, this is really good. Especially in the case of early detection, Wu Bai decoction can preserve the intestinal mucosa of dogs and prevent bleeding. The prescription can be found online. ) or stick to Smecta of 1/3.
Evening: The spirit is not bad. I have an appetite and ate 20 pieces of dog food and some nutritional cream (if the dog has no appetite, you can buy nutritional cream online, give it some nutrition, and eat it after it is cured to increase nutrition). Finally, my stool was a little thin, and I used half a pack of probiotics, half a large one, and 5 ml of Wu Bai soup.
The third morning: I was in a bad mood, very quiet, and lost my appetite, but I didn't vomit or pull. I continue to take medicine, 5ml of Wu Bai soup, half serum and half serum.
In the afternoon, I was still in a bad mood and had no appetite. I took a black stool, and then I kept taking a jelly-like stool. Medication: 1/3 smecta, 5 ml of Chinese medicine. At night: I vomited twice, and took half a tablet of Qingda, Chinese medicine and a tablet of vitamin B6.
On the fourth day, I was depressed, lost appetite, appeared jelly excrement and often vomited. I took the medicine, one tablet of vitamin B6 10 ml of Chinese medicine, half of Qingda 1/3 smecta and half of serum. It's almost the afternoon, and the vomiting has eased. I still continue to use Chinese medicine and smecta. Vomiting at night brought a little bloodshot, but it has stopped diarrhea. Medication: Qingda half, Chinese medicine 10 ml, and glucose soaked Yunnan Baiyao (if blood drawing and hematemesis are serious, it is recommended to give hemostatic drugs such as Zhixuemin, and the effect will be better. If vomiting is serious, some metoclopramide can be prepared).
The fifth day. I'm still in good spirits in the morning. I don't vomit or pull. I ate some soft dog food mixed with egg yolk and continued to use the medicine, half of which was clear and half of which was serum and traditional Chinese medicine. Continue at noon. I'm in good shape. I don't vomit or pull. I still used medicine and Chinese medicine as in the morning.
On the sixth day, I began to defecate normally, but my spirit has not fully recovered, but it has been much better. Still have to continue to give it dog food mixed with egg yolk.
Parents must make sure that their stools are normal before they can stop taking the medicine.
Wu Bai soup for prescription:
Pulsatilla 15g, Mume 15g, Coptidis Rhizoma 5g, Cortex Phellodendri 5g, Radix Curcumae 10g, and Fructus Chebulae 10g.
Prevention and treatment of canine parvovirus disease
Canine parvovirus (CPV) is a highly contagious canine infectious disease. Clinical manifestations are acute hemorrhagic enteritis and myocarditis.
First of all, pathogens
Canine parvovirus (CPV) belongs to parvovirus family. CPV has strong resistance to many physical and chemical factors and common disinfectants. 4- 10 can survive for 6 months, 37 for 2 weeks, 56 for 24 hours and 80 for 15 minutes. After being stored at room temperature for 3 months, its infectivity is only slightly reduced, and it can survive in feces for several months to several years. The virus is resistant to * * * *, chloroform and alcohols, and sensitive to ultraviolet rays, formalin, sodium hypochlorite and oxidants.
Second, epidemiology.
CPV mainly infects dogs, especially puppies, with strong infectivity and high mortality. It can happen all year round, especially in winter and spring. Sudden changes in feeding and management conditions, long-distance transportation and cold crowding can all promote the occurrence of this disease. Sick dogs are the main source of infection, and there are a lot of viruses in vomit, saliva and feces. Rehabilitation dogs can still detoxify through feces for a long time. There is evidence that people, lice, flies and cockroaches can become mechanical carriers of CPV. Healthy dogs are in direct contact with sick or poisoned dogs, or contaminated feed and drinking water are infected through the digestive tract.
Dogs are the main natural hosts, and other canines, such as coyotes, jungle dogs, crab-eating foxes and hyenas, can also be infected. With the drift of virus antigens, viruses can infect cats, bears, raccoons and other animals.
CPV infection in dogs is acute, with high mortality and often explosive epidemic. Dogs of different ages, sexes and breeds can be infected. Among dogs with clinical manifestations of vomiting and diarrhea (or hemorrhagic diarrhea), CPV infection positive dogs can account for 29.8-46.2%. Among them, dogs under 6 months old are the most susceptible to infection, accounting for 75% of the total number of CPV infected dogs, and the mortality rate of infected dogs at this age is higher than that of dogs over 6 months old. The incidence of dogs over 12 months old is relatively low. It is found that male dogs are more susceptible to infection than female dogs, but for dogs under 6 months, age, sex and breed have nothing to do with CPV infection. The survival rate of 6- 18 weeks old CPV infected dogs was studied. It was found that the titer of HI antibody was between men and women and between different age groups
Sick dogs and rehabilitation dogs with drugs are the sources of infection of this disease. The sick dog detoxifies the outside world through feces, urine, saliva and vomit; Toxic rehabilitation dogs may detoxify from feces and urine for a long time, polluting feed, drinking water, utensils and the surrounding environment [2]. However, sick dogs generally reach the peak through fecal detoxification on 7-8 days after infection, and 10- 1 1 day drops sharply. There is evidence that people, flies and cockroaches can all become mechanical carriers of CPV. It is generally believed that the transmission route of the disease is the digestive tract, and susceptible animals are mainly infected through direct or indirect contact.
The occurrence of the disease has no obvious seasonality. Generally, it occurs frequently in summer and autumn. Cold weather, sudden change of temperature, poor sanitary conditions and complicated infection will aggravate the illness and increase the mortality rate.
Third, the pathogenesis
After healthy dogs are infected with the virus through the digestive tract, the virus mainly attacks two kinds of cells, one is intestinal epithelial cells and the other is myocardial cells, which show gastrointestinal symptoms and myocarditis symptoms respectively. Myocarditis is more common in puppies.
Fourth, symptoms
The incubation period of the disease is 7- 14 days, which mostly occurs after a new environment (such as a newly bought puppy). Overeating in the bath is the inducement. Most of the disease presents enteritis syndrome and a few presents myocarditis syndrome.
Dogs with enteritis are depressed, anorexia and occasional fever. At first, they have soft stools or slight vomiting, and then they develop into frequent vomiting and severe diarrhea. At first, the stool was gray, yellow or milky white, with jelly-like mucus, and then the foul-smelling soy sauce-like or tomato juice-like bloody stool was discharged. The sick dog quickly dehydrated, emaciated, sunken eyes, messy fur, inelastic skin, cold ears and limbs, high depression and shock and died. From mild symptoms to severe symptoms at the initial stage of the disease, it generally does not exceed 2 days, and the whole course of disease generally does not exceed one week.
Myocarditis is more common in puppies aged 4-6 weeks, often without premonitory symptoms, or only with mild diarrhea, and then suddenly weak, groaning, cyanosis of mucous membrane, extremely difficult breathing, fast and weak pulse, murmur in heart auscultation, and often death within a few hours.
Verb (abbreviation of verb) diagnosis
Diagnosis can be made according to epidemic symptoms and serological reaction. The disease is characterized by rapid onset, strong infectivity and frequent local outbreaks. On-site manifestations are enteritis syndrome such as vomiting, diarrhea and dehydration, and the mortality rate is high. Enzyme-linked immunosorbent assay (ELISA) is widely used in serological reactions, and its kits are available at home and abroad. This method has mature technology and high detection rate.
Sixth, treatment.
Apply antibody, resist bacteria and virus, diminish inflammation, stop bleeding and stop vomiting; Clean up the gastrointestinal tract, mediate gastrointestinal function and prescribe the right medicine.
The early application of specific therapies such as (1) antibody, monoclonal antibody against canine parvovirus, immunoglobulin, Erlianwang, Qianglikang and Erliangaomian serum, the earlier the clinical application, the better the therapeutic effect.
(2) Symptomatic treatment: rehydration, hemostasis, antiemetic, antibacterial and anti-inflammatory to prevent secondary infection. Available: Gabby Antibacterial, Li En, Du Yan 120, Tianxiang Fuke, Ofloxacin, Ceftriaxone Sodium, Maoquanling, Xiaoyan Zhili Decoction, etc. For symptomatic treatment. Most sick dogs die of diarrhea and dehydration, so fluid replacement is the main measure to treat this disease. We should strictly control the infusion volume and infusion speed and pay attention to the function of the heart, otherwise it will easily lead to treatment failure. When sick dogs have severe vomiting and diarrhea, dehydration, electrolyte disorder and acid-base balance need to be corrected. Ringer's lactate solution, 25% glucose solution and anisodamine hydrochloride injection can be injected intravenously twice a day.
(3) Oral rehydration method When the sick dog shows no eating, rapid heart rate, no vomiting, appetite or thirst, oral rehydration salt can be given: any dog can drink water freely or have deep enema.
(4) Blood transfusion therapy has a good therapeutic effect on this disease; Albumin and amino acids can be infused in combination with traditional Chinese medicine.
Seven. prevent
CPV has strong resistance to the outside world and long survival time, so it is highly contagious. Once the disease occurs, the sick dog should be isolated quickly, and the feeding utensils, utensils and vehicles contaminated by the sick dog should be strictly disinfected. Disinfectant can be 2% sodium hydroxide, bleaching powder, potassium hypochlorite, etc. It seems that ultraviolet rays can be used for disinfection. I stopped using it for two weeks. The breeder should strictly disinfect, limit the flow and avoid indirect infection.
Vaccination is the fundamental measure to prevent the epidemic. However, immune failure may occur, which is related to vaccine quality and immune interference. Mainly due to the improper selection of vaccine strains and the interference of maternal antibodies. The quality of the vaccine should be reliable, and the first immunization time is generally considered to be around 10 week. However, considering that puppies are susceptible before 10 week, dogs can be injected with bivalent vaccine (which can break through the interference of maternal antibodies) at 6 weeks, hexavalent vaccine at 10 week, and then 1 time hexavalent vaccine every three weeks. Thank you for taking it as the best answer. Give points.